Clinical characteristics of pediatric hidradenitis suppurativa: a cross-sectional multicenter study of 140 patients

Autor: Amelia Głowaczewska, Lukasz Matusiak, Mateja Dolenc-Voljč, Nayera H. Moftah, Jorge Romaní, V. Sigsgaard, Burcu Beksaç, Jan Lapins, Hessel H. van der Zee, Moetaz El-Domyati, Errol P. Prens, Eugènia Agut-Busquet, Axel Patrice Villani, Lerinza van den Worm, Mehmet Ali Gürer, Lennart Emtestam, Hassan Riad Kottb, Annika M J D Vanlaerhoven, Farida Benhadou, Maïa Delage-Toriel, Lisa Weibel, Hossam Abdel-Wahab, José C. Pascual, Ditte Marie Saunte, Vincenzo Bettoli, Véronique Del Marmol, Thi Lam, Dorra Bouazzi, Giada Calamo, Mohammad Fatani, Pierre-Andre Becherel, Martin Theiler, Peter Theut Riis, Jacek C Szepietowski, Aude Nassif, Philippe Guillem, Rania Abdelghani, Carol Hlela, Nejib Doss, Gregor B.E. Jemec, Naomi N Kappe
Přispěvatelé: Zealand University Hospital [Roskilde, Denmark], University of Copenhagen = Københavns Universitet (UCPH), Service de dermatologie [HCL Lyon], Hôpital Edouard Herriot [CHU - HCL], Hospices Civils de Lyon (HCL)-Hospices Civils de Lyon (HCL), Clinique du Val d'Ouest, Hospital Universitario de Alicante, Instituto de Investigación Sanitaria y Biomédica de Alicante (ISABIAL-FISABIO), Fundación para el Fomento de la Investigación Sanitaria y Biomédica de la Comunitat Valenciana [Espagne] (FISABIO), Erasmus University Medical Center [Rotterdam] (Erasmus MC), Minia University, Al-Azhar University [Cairo, Egypt], Armed Forces College of Medicine [Cairo, Egypt] (AFCM), Universitat Autònoma de Barcelona (UAB), Hospital de la Santa Creu i Sant Pau, Hospital Universitari Parc Taulí of Sabadell, Barcelona, University of Cape Town, Red Cross Children's Hospital [Cape Town, South Africa], Azienda Ospedaliero Universitaria di Ferrara [Cona, Italy], Gazi University, Wrocław Medical University, Karolinska Institutet [Stockholm], Hamad medical corporation, Hera General Hospital [Makkah, Saudi Arabia], University Children’s Hospital Zurich, University hospital of Zurich [Zurich], Centre Médical de l'Institut Pasteur (CMIP), Institut Pasteur [Paris] (IP), Hôpital privé d’Antony, University of Ljubljana, University Medical Centre Ljubljana [Ljubljana, Slovenia] (UMCL), Department of Dermatology, Military Hospital of Tunis, Hôpital militaire de Tunis, Hôpital Erasme [Bruxelles] (ULB), Faculté de Médecine [Bruxelles] (ULB), Université libre de Bruxelles (ULB)-Université libre de Bruxelles (ULB), Université libre de Bruxelles (ULB), University of Copenhagen = Københavns Universitet (KU), Wroclaw Medical University [Wrocław, Pologne], Centre Médical de l'Institut Pasteur, Institut Pasteur [Paris], Dermatology
Jazyk: angličtina
Rok vydání: 2020
Předmět:
Male
Hirsutism
[SDV]Life Sciences [q-bio]
Dermatologic Surgical Procedures
Administration
Oral
Disease
Comorbidity
Severity of Illness Index
Body Mass Index
030207 dermatology & venereal diseases
0302 clinical medicine
Risk Factors
Acne Vulgaris
Medicine
Hidradenitis suppurativa
Child
Children
Acne
hirsutism
Pediatric
medicine.diagnostic_test
Clindamycin
Smoking
General Medicine
Sciences bio-médicales et agricoles
3. Good health
Anti-Bacterial Agents
Treatment Outcome
030220 oncology & carcinogenesis
Drug Therapy
Combination
Female
Rifampin
medicine.drug
medicine.medical_specialty
Adolescent
Physical examination
Dermatology
Administration
Cutaneous
03 medical and health sciences
Young Adult
Pilonidal Sinus
Internal medicine
Humans
Obesity
business.industry
Resorcinols
Acne inversa
Tetracycline
medicine.disease
Cross-Sectional Studies
business
Rifampicin
[SDV.MHEP]Life Sciences [q-bio]/Human health and pathology
[SDV.MHEP.DERM]Life Sciences [q-bio]/Human health and pathology/Dermatology
Zdroj: Archives of Dermatological Research
Archives of Dermatological Research, 2020, 1, ⟨10.1007/s00403-020-02053-6⟩
Archives of dermatological research, 312 (10
ARCHIVES OF DERMATOLOGICAL RESEARCH
r-IIB SANT PAU. Repositorio Institucional de Producción Científica del Instituto de Investigación Biomédica Sant Pau
instname
Archives of Dermatological Research, Springer Verlag, 2020, 1, ⟨10.1007/s00403-020-02053-6⟩
r-ISABIAL. Repositorio Institucional de Producción Científica del Instituto de Investigación Biomédica y Sanitaria de Alicante
Archives of Dermatological Research, 312(10), 715-724. Springer-Verlag
ISSN: 1432-069X
0340-3696
Popis: Hidradenitis suppurativa (HS) rarely affects pediatric patients. The literature on pediatric HS patients is scarce. This is a cross-sectional study based on case note review or interviews and clinical examination of 140 pediatric patients undergoing secondary or tertiary level care. Patients were predominantly female (75.5%, n = 105) with a median age of 16. 39% reported 1st-degree relative with HS. Median BMI percentile was 88, and 11% were smokers (n = 15). Median modified Sartorius score was 8.5. Notable comorbidities found were acne (32.8%, n = 45), hirsutism (19.3%, n = 27), and pilonidal cysts (16.4%, n = 23). Resorcinol (n = 27) and clindamycin (n = 25) were the most frequently used topical treatments. Patients were treated with tetracycline (n = 32), or oral clindamycin and rifampicin in combination (n = 29). Surgical excision was performed in 18 patients, deroofing in five and incision in seven patients. Obesity seemed to be prominent in the pediatric population and correlated to parent BMI, suggesting a potential for preventive measures for the family. Disease management appeared to be similar to that of adult HS, bearing in mind that the younger the patient, the milder the disease in majority of cases.
info:eu-repo/semantics/published
Databáze: OpenAIRE
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