Controlling the fluoride dosage in a patient with compromised salivary function
| Autor: | Naomi Eidelman, Clifton M. Carey, Frederick C. Eichmiller |
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| Rok vydání: | 2005 |
| Předmět: |
Male
Fluoride Poisoning medicine.medical_specialty Gastrointestinal Diseases medicine.medical_treatment Urinary system Xerostomia Fluorides chemistry.chemical_compound Fluoride toxicity Swallowing medicine Humans Musculoskeletal Diseases General Dentistry Chemotherapy business.industry Middle Aged Arthralgia Cariostatic Agents Surgery Regimen chemistry Anesthesia Toxicity Cranial Irradiation business Fluoride |
| Zdroj: | The Journal of the American Dental Association. 136:67-70 |
| ISSN: | 0002-8177 |
| Popis: | Background High-concentration topical fluorides are used commonly to prevent caries in patients with compromised salivary function due to irradiation and chemotherapy. Case Description The authors describe a 50-year-old man with previously treated cancer who was using tray-applied topical fluoride gel. He complained of gastric symptoms, difficulty in swallowing, leg muscle soreness and knee joint soreness. A computed tomographic scan revealed thickening of the esophageal walls. An upper endoscopy revealed abnormal motility. The motility test indicated high-amplitude peristalsis and hypertensive lower esophageal sphincter, and urine testing indicated high levels of systemic fluoride. The patient's fluoride regimen was altered, and within a short period his urinary fluoride levels returned to normal and his symptoms resolved. Clinical Implications Clinicians prescribing home-applied high-concentration fluorides need to be cognizant of the symptoms of fluoride toxicity, carefully monitor the patient's compliance with the treatment regimen, and adjust the dosage or mode of application to control the total ingested dose of fluoride. |
| Databáze: | OpenAIRE |
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