The Experience of a Novel Glycylcycline Antibiotic for a Patient with Infection Caused by Multiple Drug-Resistant Pathogens: What is the Benefit?
| Autor: | Yu-Ling Weng, Chung-Lieh Hung, Po-Chin Chi, Ching-Chi Lin, Shih-Yi Lee, Chien-Liang Wu |
|---|---|
| Rok vydání: | 2008 |
| Předmět: |
medicine.medical_specialty
Imipenem Ceftazidime Tigecycline lcsh:Geriatrics Glycylcycline ventilator-associated pneumonia chemistry.chemical_compound Medicine Intensive care medicine biology business.industry Sulbactam biochemical phenomena metabolism and nutrition bacterial infections and mycoses biology.organism_classification Acinetobacter baumannii lcsh:RC952-954.6 chemistry Linezolid Colistin tigecycline Geriatrics and Gerontology business multiple antibacterial drug resistance medicine.drug |
| Zdroj: | International Journal of Gerontology, Vol 2, Iss 3, Pp 124-127 (2008) |
| ISSN: | 1873-9598 |
| DOI: | 10.1016/s1873-9598(08)70050-4 |
| Popis: | SUMMARY We report a 75-year-old man with septic shock induced by ventilator-associated pneumonia caused by multiple drug-resistant Acinetobacter baumannii and catheter-related infection by vancomycin-resistant enterococci. He failed to respond to the initial management, including antibiotics (linezolid, imipenem, sulbactam and colistin) and hemodynamic-guided fluid challenge. However, his condition improved dramatically after the antibiotic regimen was changed to tigecycline and ceftazidime. In addition to the superiority of the antibacterial effect of tigecycline, fluid control can be achieved more easily while using a single antibiotic instead of multiple drugs, which is also important for care of a critically ill elderly man with compromised cardiorespiratory or renal function. Here, we present a patient infected with multiple drug-resistant pathogens, who improved clinically after being treated with tigecycline, to demonstrate the benefits of this antibiotic. (International Journal of Gerontology 2008; 2(3): 124-127) |
| Databáze: | OpenAIRE |
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