Diagnostic role of coronary calcium scoring in the rapid access chest pain clinic: prospective evaluation of NICE guidance

Autor: Alain Dumo, Avijit Lahiri, Shreenidhi Venuraju, S. Richard Underwood, Deven Patel, Roby Rakhit, Ajay Yerramasu, David Lipkin
Rok vydání: 2014
Předmět:
Zdroj: European Heart Journal - Cardiovascular Imaging. 15:886-892
ISSN: 2047-2412
2047-2404
DOI: 10.1093/ehjci/jeu011
Popis: Background Coronary artery calcium (CAC) imaging by unenhanced computed X-ray tomography (CT) is recommended as an initial diagnostic test for patients with stable chest pain symptoms but a low likelihood (10–29%) of underlying obstructive coronary artery disease (CAD) after clinical assessment. The recommendation has not previously been tested prospectively in a rapid access chest pain clinic (RACPC). Methods We recruited 300 consecutive patients presenting with stable chest pain to the RACPC of three hospitals. All patients underwent CAC imaging, followed by invasive coronary angiography (ICA) in patients with CAC ≥1000Agatston units (Au) and CT coronary angiography (CTCA) in those with CAC 400 Au have a high prevalence of obstructive CAD and further investigation with ICA or functional imaging may be warranted rather than CTCA. These findings support NICE guidance for the investigation of stable chest pain. ClinicalTrials. gov Identifier NCT01464203
Databáze: OpenAIRE