Alcohol Consumption and Risk of Chronic Kidney Disease: A Nationwide Observational Cohort Study
Autor: | Yu Kai Lin, Yu-Yen Chen, Yung Feng Yen, Yun Ju Lai, Chung Yeh Deng, Chu Chieh Chen |
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Jazyk: | angličtina |
Rok vydání: | 2019 |
Předmět: |
Adult
Male medicine.medical_specialty Alcohol Drinking Databases Factual Taiwan 030232 urology & nephrology lcsh:TX341-641 030204 cardiovascular system & hematology Article Cohort Studies 03 medical and health sciences 0302 clinical medicine Risk Factors Internal medicine Epidemiology cohort study medicine Humans National Health Interview Survey Renal Insufficiency Chronic Nutrition and Dietetics alcohol business.industry Incidence Public health Incidence (epidemiology) Hazard ratio Middle Aged medicine.disease Population study Female business lcsh:Nutrition. Foods and food supply chronic kidney disease Food Science Kidney disease Cohort study |
Zdroj: | Nutrients; Volume 11; Issue 9; Pages: 2121 Nutrients, Vol 11, Iss 9, p 2121 (2019) Nutrients |
ISSN: | 2072-6643 |
DOI: | 10.3390/nu11092121 |
Popis: | Alcohol consumption is a significant public health issue worldwide. The rat model and epidemiological studies have both reported conflicting results about the effects of alcohol on the kidneys. We aimed to explore the relationships between alcohol consumption and chronic kidney disease. Data from the National Health Interview Survey, the National Health Insurance research database, and the National Deaths Dataset were used. Standardized in-person interviews were executed in 2001, 2005, and 2009 to obtain the demographic characteristics of study population. The participants were followed up until 2013. The primary outcome was new-onset chronic kidney disease. We analyzed 45,200 adults older than 18 years (50.8% men and 49.2% women), and the overall mean (SD) age was 42.73 (16.64) years. During the 8.5 (3.5) years of follow-up, new-onset chronic kidney disease was recognized in 1535 (5.5%), 292 (2.7%), and 317 (4.9%) non-drinking, social-drinking, and regular-drinking participants, respectively. The participants who were social and regular drinkers had a significantly decreased risk of chronic kidney disease incidence (social drinking: adjusted hazard ratio (HR), 0.85; 95% confidence interval (CI), 0.74−0.97; p = 0.018; regular-drinking: AHR, 0.85; 95% CI, 0.74−0.98; p = 0.024), with baseline demographics and comorbidities adjusted. In conclusion, social and regular drinkers had decreased risk of chronic kidney disease when compared with non-drinkers. |
Databáze: | OpenAIRE |
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