| Autor: |
Jon B. Patteson, Camille Marie Fortinez, Andrew T. Putz, Juan Rodriguez-Rivas, L. Henry Bryant, Kamal Adhikari, Martin Weigt, T. Martin Schmeing, Bo Li |
| Rok vydání: |
2022 |
| Předmět: |
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| Zdroj: |
Journal of the American Chemical Society. 144(31) |
| ISSN: |
1520-5126 |
| Popis: |
Dehydroamino acids are important structural motifs and biosynthetic intermediates for natural products. Many bioactive natural products of nonribosomal origin contain dehydroamino acids; however, the biosynthesis of dehydroamino acids in most nonribosomal peptides is not well understood. Here, we provide biochemical and bioinformatic evidence in support of the role of a unique class of condensation domains in dehydration (C |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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