Effect of Melatonin on Cellular Composition of the Spleen and Parameters of Lipid Metabolism in Rats with Alimentary Obesity
| Autor: | S. V. Michurina, V. A. Trufakin, M. V. Khrapova, E. V. Mel’nikova, M. V. Tenditnik, M. I. Dushkin, A. V. Shurlygina, N. G. Panteleeva |
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| Rok vydání: | 2014 |
| Předmět: |
medicine.medical_specialty
Drug Evaluation Preclinical Spleen Biology Diet High-Fat General Biochemistry Genetics and Molecular Biology Melatonin Leukocyte Count Immune system Internal medicine medicine Animals Immunologic Factors Lymphocytes Obesity Rats Wistar Triglycerides Immune status Cellular composition Alimentary obesity Lipid metabolism General Medicine biochemical phenomena metabolism and nutrition Lipid Metabolism medicine.disease Cholesterol Endocrinology medicine.anatomical_structure Liver bacteria Female Lymph Nodes hormones hormone substitutes and hormone antagonists medicine.drug |
| Zdroj: | Bulletin of Experimental Biology and Medicine. 158:42-45 |
| ISSN: | 1573-8221 0007-4888 |
| DOI: | 10.1007/s10517-014-2687-6 |
| Popis: | We studied the effects of melatonin on the status of immune organs and parameters of lipid metabolism in rats with alimentary obesity and parameters of lipid metabolism and immune status in Wistar rats kept on high-fat diet and receiving melatonin solution per os. Melatonin leveled the changes in blood and liver parameters of lipid metabolism, which was paralleled by normalization of cellular composition of immune organs. We conclude that melatonin can be a promising agent for the treatment of lipid metabolism and immune status disorders in alimentary obesity. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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