Marchiafava-Bignami disease: diffusion-weighted MRI in corpus callosum and cortical lesions
| Autor: | P. Meneegon, I. Sibon, C. Pachai, J. M. Orgogozo, V. Dousset |
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| Rok vydání: | 2005 |
| Předmět: |
Adult
Male Pathology medicine.medical_specialty Corpus callosum Nerve Fibers Myelinated Corpus Callosum Alcohol-Induced Disorders Nervous System Predictive Value of Tests medicine Effective diffusion coefficient Humans Alcohol-Induced Disorders Cerebral Cortex Ethanol Neurodegenerative Diseases Marchiafava–Bignami disease Middle Aged medicine.disease Prognosis Alcoholism Diffusion Magnetic Resonance Imaging nervous system Clinical diagnosis Female Neurology (clinical) Psychology Cognition Disorders Wallerian Degeneration Diffusion MRI |
| Zdroj: | Neurology. 65(3) |
| ISSN: | 1526-632X |
| Popis: | The clinical diagnosis of Marchiafava-Bignami disease (MBD) can be difficult. Acute demyelination of the corpus callosum is characteristic of the disease. The authors report the use of MR diffusion-weighted imaging (DWI) in six cases of acute MBD. They show that apparent diffusion coefficient restriction of the corpus callosum and cortical lesions were associated with a higher mortality rate and more severe cognitive sequelae. |
| Databáze: | OpenAIRE |
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