Epidemiology of onychomycosis in Serbia: a laboratory-based survey and risk factor identification
| Autor: | Eleonora Dubljanin, Aleksandar Džamić, Sanja Mitrović, Isidora S. Vujcic, Valentina Arsić Arsenijević, Sandra Sipetic Grujicic, Ivana Čolović Čalovski |
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| Rok vydání: | 2016 |
| Předmět: |
Adult
Male 0301 basic medicine Pediatrics medicine.medical_specialty Adolescent 030106 microbiology Hyperkeratosis Dermatology Trichophyton rubrum Young Adult 030207 dermatology & venereal diseases 03 medical and health sciences 0302 clinical medicine Trichophyton Risk Factors Surveys and Questionnaires Yeasts Onychomycosis Epidemiology Dermatomycoses Humans Hyperhidrosis Medicine Family history Risk factor Child Aged Aged 80 and over biology business.industry Direct microscopy Age Factors Keratosis General Medicine Middle Aged medicine.disease biology.organism_classification 3. Good health Infectious Diseases Nails Child Preschool Etiology Population study Female business Serbia |
| Zdroj: | Mycoses. 60:25-32 |
| ISSN: | 0933-7407 |
| DOI: | 10.1111/myc.12537 |
| Popis: | Onychomycosis is a fungal infection of the fingernails and/or toenails caused by dermatophytes, yeasts and non-dermatophyte moulds. The epidemiology of onychomycosis in Serbia is yet to be fully established. This epidemiological study was aimed at evaluating the epidemiology of onychomycosis in a sample of the Serbian patients at risk of onychomycosis, to determine the fungal aetiological agents and to identify the possible risk factors. The study population included 374 patients from six centres in Serbia with suspected onychomycosis. Demographic data, data about comorbidities, lifestyle, clinical aspects of onychomycosis, trauma, excessive perspiration and personal and family history of previous onychomycosis were studied. Laboratory confirmation of diagnosis was done by direct microscopy, fungal culture and PCR. Diagnosis of onychomycosis was confirmed in 50.8% of patients, who tested positive to at least one laboratory test (direct microscopy, fungal culture or PCR). Trichophyton rubrum was predominant both on toenails (85.98%) and on fingernails (38.46%). Independent risk factors for onychomycosis were: old age (OR = 2.285; P < 0.001), family history of previous onychomycosis and/or tinea pedis (OR = 2.452; P = 0.005), excessive perspiration (OR = 2.165; P = 0.002) and higher degree of hyperkeratosis (OR = 1.755; P = 0.020). This is a first epidemiological study of onychomycosis from Serbia. |
| Databáze: | OpenAIRE |
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