A comparison of the efficacy of Cetirizine and terfenadine
| Autor: | C. Betteli, Andri G, P Mezzelani, L. Andri, Gianenrico Senna, S. Givanni, C. Lombardi |
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| Rok vydání: | 1993 |
| Předmět: |
Adult
medicine.medical_specialty Chemotherapy Urticaria business.industry Visual analogue scale medicine.medical_treatment Immunology Parallel study Cetirizine Double blind Double-Blind Method Internal medicine Anesthesia Chronic Disease medicine Humans Immunology and Allergy Patient evaluation Terfenadine Chronic idiopathic urticaria business medicine.drug |
| Zdroj: | Allergy. 48:358-365 |
| ISSN: | 1398-9995 0105-4538 |
| DOI: | 10.1111/j.1398-9995.1993.tb02406.x |
| Popis: | In a 20-d, double-blind, randomized, parallel study, the efficacy of cetirizine and terfenadine was compared in 30 patients with chronic idiopathic urticaria. Subjects were randomly divided into two 15-patient groups. The first group was given cetirizine (10 mg once daily); the second terfenadine (60 mg twice daily). Cetirizine proved to be more effective than terfenadine in controlling urticaria symptoms. In fact, the score of the investigators' overall assessment was significantly lower in the cetirizine-treated group than in the terfenadine-treated group. Moreover, patient evaluation by a visual analog scale and symptoms assessed on a 4-point scale showed a better improvement in the cetirizine group. The number and severity of side-effects were similar in both treatment groups. |
| Databáze: | OpenAIRE |
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