Popis: |
Osteonecrosis is defined as “necrosis of bone due to obstruction of its blood supply” [1]. Although osteonecrosis of the jaw (ONJ) can be occur spontaneous or idiopathic, etiologic agents most often serve as modifiers for a specific case of ONJ. ONJ can result from radiation therapy to the head and neck, chronic corticosteroid use, herpes zoster virus infection in immunocompromised patients, anti-angiogenesis medications, uncontrolled infections or major trauma, and antiresorptive medications |