PET/MRI of atherosclerosis
| Autor: | Claudia Prieto, M. Eline Kooi, Rik P. M. Moonen, René M. Botnar, Jochem A. J. van der Pol, Mueez Aizaz |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2020 |
| Předmět: |
medicine.medical_specialty
IMAGE-BASED NAVIGATORS ZERO-ECHO-TIME RISK PLAQUE FEATURES 030204 cardiovascular system & hematology medicine.disease_cause RESPIRATORY MOTION-COMPENSATION 18F-SODIUM FLUORIDE UPTAKE 030218 nuclear medicine & medical imaging Coronary artery disease 03 medical and health sciences 0302 clinical medicine POSITRON-EMISSION-TOMOGRAPHY vascular CAROTID PLAQUE hybrid imaging medicine Myocardial infarction Stroke CORONARY MR-ANGIOGRAPHY medicine.diagnostic_test business.industry Fibrous cap Review Article on Advanced Imaging in The Diagnosis of Cardiovascular Diseases medicine.disease Atherosclerosis Vulnerable plaque ATTENUATION CORRECTION 3. Good health Coronary arteries Soft tissue contrast medicine.anatomical_structure PET/MRI Positron emission tomography 1ST CLINICAL-EXPERIENCE Radiology vulnerable plaque Cardiology and Cardiovascular Medicine business |
| Zdroj: | Cardiovascular Diagnosis and Therapy Cardiovasc Diagn Ther |
| ISSN: | 2223-3652 |
| Popis: | Myocardial infarction and stroke are the most prevalent global causes of death. Each year 15 million people worldwide die due to myocardial infarction or stroke. Rupture of a vulnerable atherosclerotic plaque is the main underlying cause of stroke and myocardial infarction. Key features of a vulnerable plaque are inflammation, a large lipid-rich necrotic core (LRNC) with a thin or ruptured overlying fibrous cap, and intraplaque hemorrhage (IPH). Noninvasive imaging of these features could have a role in risk stratification of myocardial infarction and stroke and can potentially be utilized for treatment guidance and monitoring. The recent development of hybrid PET/MRI combining the superior soft tissue contrast of MRI with the opportunity to visualize specific plaque features using various radioactive tracers, paves the way for comprehensive plaque imaging. In this review, the use of hybrid PET/MRI for atherosclerotic plaque imaging in carotid and coronary arteries is discussed. The pros and cons of different hybrid PET/MRI systems are reviewed. The challenges in the development of PET/MRI and potential solutions are described. An overview of PET and MRI acquisition techniques for imaging of atherosclerosis including motion correction is provided, followed by a summary of vessel wall imaging PET/MRI studies in patients with carotid and coronary artery disease. Finally, the future of imaging of atherosclerosis with PET/MRI is discussed. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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