Vascular branching point counts using photoacoustic imaging in the superficial layer of the breast: A potential biomarker for breast cancer

Autor: Yasufumi Asao, Kaori Togashi, Aya Yoshikawa, Tsuyoshi Shiina, Takayuki Yagi, Yoshiaki Matsumoto, Masahiro Kawashima, Takaki Sakurai, Hironori Haga, Toshifumi Fukui, Masae Torii, Elham Fakhrejahani, Masahiro Takada, Mariko Tokiwa, Masako Kataoka, Masakazu Toi, Nobuko Kawaguchi-Sakita, Shotaro Kanao, Yoshie Nakayama, Iku Yamaga
Rok vydání: 2018
Předmět:
BP
blood pressure

medicine.drug_class
lcsh:QC221-246
Photoacoustic imaging in biomedicine
01 natural sciences
030218 nuclear medicine & medical imaging
010309 optics
03 medical and health sciences
Breast cancer
0302 clinical medicine
0103 physical sciences
medicine
lcsh:QC350-467
Radiology
Nuclear Medicine and imaging

In patient
DCIS
ductal carcinoma in situ

skin and connective tissue diseases
US
ultrasonography

business.industry
VBP
vessel branching point

Vessel branching points
Cancer
Biomarker
Branching points
medicine.disease
lcsh:QC1-999
Atomic and Molecular Physics
and Optics

HDA
hemispherical detector array

PAI
photoacoustic imaging

Estrogen
Potential biomarkers
lcsh:Acoustics. Sound
Vasculature
Biomarker (medicine)
Photoacoustic imaging
Nuclear medicine
business
MRI
magnetic resonance imaging

lcsh:Physics
lcsh:Optics. Light
Research Article
Zdroj: Photoacoustics, Vol 11, Iss, Pp 6-13 (2018)
Photoacoustics
ISSN: 2213-5979
DOI: 10.1016/j.pacs.2018.06.002
Popis: This study aimed to identify the characteristics of the vascular network in the superficial subcutaneous layer of the breast and to analyze differences between breasts with cancer and contralateral unaffected breasts using vessel branching points (VBPs) detected by three-dimensional photoacoustic imaging with a hemispherical detector array. In 22 patients with unilateral breast cancer, the average VBP counts to a depth of 7 mm below the skin surface were significantly greater in breasts with cancer than in the contralateral unaffected breasts (p
Databáze: OpenAIRE