Diagnosis and assessment of apathy in Chinese patients with Alzheimer's disease
| Autor: | Zhongxin Zhao, Maurice Preter, Liuqing Huang, Hongyi Zhao |
|---|---|
| Rok vydání: | 2011 |
| Předmět: |
Male
medicine.medical_specialty China Cross-sectional study Apathy Neuropsychological Tests Severity of Illness Index Asian People Alzheimer Disease Severity of illness medicine Prevalence Dementia Humans Psychiatry Depression (differential diagnoses) Aged Aged 80 and over Mini–Mental State Examination medicine.diagnostic_test Reproducibility of Results Caregiver burden Middle Aged medicine.disease Psychiatry and Mental health Clinical Psychology Cross-Sectional Studies Caregivers Major depressive disorder Female medicine.symptom Psychology Clinical psychology |
| Zdroj: | Journal of psychosomatic research. 72(5) |
| ISSN: | 1879-1360 |
| Popis: | Background Apathy is a major component of the behavioral and psychological symptoms of Alzheimer's Disease (AD) and other types of dementia. Most researchers have reached a consensus on a new set of diagnostic criteria for apathy (DCA) recently. However, no relevant reports on apathy exist for AD patients in Asian countries yet. Objectives To estimate the prevalence of apathy in Chinese AD patients. Methods 83 AD patients were recruited for a cross-sectional observational study. Following the new diagnostic criteria for apathy (DCA) and DSM-IV criteria for Major Depressive Disorder (MDD), each patient was assessed successively by Mini Mental State Examination (MMSE), the Neuropsychiatric Inventory-apathy subscale (NPI-apathy), the Geriatric Depression Screening scale (GDS), and the Caregiver Burden Scale (CBS). Results According to the DCA, we found that the frequency of apathy in Chinese AD patients reached 61.4%. The DCA had very good standard validity and internal consistency. The frequency of apathy was not significantly associated with that of depression, whereas there was a significant association between apathy and more severe cognitive deficits. Caregiver burden was significantly associated with severity of apathy. Conclusions From the symptoms of a group of Chinese AD patients, we summarized a set of effective methods for the diagnosis and assessment of apathy. |
| Databáze: | OpenAIRE |
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