Variant angina associated with coronary artery endothelial dysfunction and myocardial bridge: a case report and review of the literature
| Autor: | Alessandro Lupi, Edoardo Verna, Andrea Rognoni, Gabriele Iraghi, Gioel Gabrio Secco, Federico Nardi, Stefano Bertuol, Angelo S. Bongo |
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| Rok vydání: | 2011 |
| Předmět: |
Myocardial bridge
Adult Angina Pectoris Variant Male Acute coronary syndrome medicine.medical_specialty Endothelium Myocardial bridging Myocardial Bridging Angina Internal medicine Internal Medicine medicine Humans cardiovascular diseases Endothelial dysfunction business.industry General Medicine medicine.disease Coronary Vessels medicine.anatomical_structure Bridge (graph theory) Cardiology Endothelium Vascular business Artery |
| Zdroj: | Internal medicine (Tokyo, Japan). 50(21) |
| ISSN: | 1349-7235 |
| Popis: | The association of variant angina (VA) and myocardial bridges is a rare finding. We describe a case of VA with recurrent coronary spasm triggered by different stimuli at the site of a myocardial bridge. The interplay of endothelial dysfunction, coronary vasoconstriction and myocardial bridging was detected by intracoronary acetylcholine test and IVUS. We speculate that mechanical stimulation at the bridge site caused endothelial dysfunction and enhanced local susceptibility to vasoconstrictor stimuli. Variant angina should always be suspected in cases of ST-elevation acute coronary syndrome without any significant angiographic coronary stenosis. |
| Databáze: | OpenAIRE |
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