Isradipine in Asian Patients with Hypertension
| Autor: | S. Hussain, M. Zubair, S. Karim |
|---|---|
| Rok vydání: | 1990 |
| Předmět: |
Adult
Male medicine.medical_specialty Pyridines Pharmacology toxicology Sitting Pharmacotherapy Internal medicine medicine Humans Pakistan Single-Blind Method Pharmacology (medical) Antihypertensive Agents Isradipine business.industry Mean age Middle Aged Standing diastolic blood pressure Standing systolic blood pressure Surgery Hypertension Cardiology Female business medicine.drug |
| Zdroj: | Drugs. 40:26-29 |
| ISSN: | 0012-6667 |
| DOI: | 10.2165/00003495-199000402-00008 |
| Popis: | Isradipine, a new calcium antagonist, was administered to 51 Pakistani patients with hypertension (36 women, 15 men; mean age 47 years) over an 8-week period. Mean sitting systolic, and sitting and standing diastolic blood pressure was significantly reduced, and mean standing systolic blood pressure tended to decrease. Laboratory values, and both sitting and standing heart rates were not significantly affected by isradipine treatment. At the end of 8 weeks, 41.2% of patients were receiving isradipine 1.25mg twice daily, and 58.8% were receiving 2.5mg twice daily. Isradipine was found to be effective and well tolerated in Pakistani patients with mild to moderate hypertension. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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