Diagnostic performance of nocturnal oximetry in the detection of obstructive sleep apnea syndrome: a Brazilian study

Autor: Analúcia Abreu Maranhão, Luciane Velasque, Maria Helena de Araújo-Melo, Denise Duprat Neves, Julio Cezar Rodrigues Filho
Rok vydání: 2020
Předmět:
Zdroj: Sleep and Breathing. 24:1487-1494
ISSN: 1522-1709
1520-9512
DOI: 10.1007/s11325-019-02000-4
Popis: Due to the increasing prevalence of obstructive sleep apnea (OSA), more practical diagnostic methods than polysomnography (PSG) have become necessary. This research aims to analyze the performance of nocturnal oximetry (NO) in the diagnosis of OSA.In this cross-sectional study, we analyzed 41 variables provided by the oximetry of all PSG performed by the LabSono of University Hospital Gaffrée and Guinle, a total of 83 exams. We evaluated the correlation coefficients (Spearman) between these data and the Apnea/Hypopnea Index (AHI) and then calculated the diagnostics performances, by the area under the curve (ROC) (AUC), of the best correlated variables and their respective cutoffs, in the identification of an AHI ≥ 15/h.Virtually all oximetric data showed good correlations with AHI, except for some temporal data. We chose 5 of them and calculated their diagnostic performances. T90% shows AUC of 0.904 (0.835-0.972) and, at cutoff19 min, a sensitivity (Sens.) of 75.68% and specificity (Spec.) of 95.65%. DO3/10Total, AUC 0.936 (0.888-0.989), and at the cutoff51 has Sens. 97.3% and Spec. 76.09%. ODI3/10/h has AUC 0.932 (0.884-0.988), at the cutoff7/h, Sens. 97.3% and Spec. 78.26%. DO4/5Total AUC 0.932 (0.882-0.981), at the cutoff64 has Sens. 86.49% and Spec. 82.61% and ODI4/5/h has AUC 0.930 (0.880-0.981), the cutoff5.69/h Sens. 97.3% and Spec. 73.91%.Our study concludes that NO is accurate in identifying AHI15/h, and provides reliable information on PSG replacement, which could make the diagnosis of OSA cheaper and more comfortable.
Databáze: OpenAIRE
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