Familial complete androgen insensitivity syndrome with prostatic tissue and seminal vesicles
| Autor: | Pramod Kumar Palai, Kalpalata Tripathy, Kalyaniprava Gouda, Lucy Das |
|---|---|
| Rok vydání: | 2010 |
| Předmět: |
Male
medicine.medical_specialty Uterus urologic and male genital diseases Mesonephric duct Young Adult Complete androgen insensitivity syndrome Prostate Internal medicine Testis Medicine Humans Cervix business.industry Obstetrics and Gynecology General Medicine Androgen-Insensitivity Syndrome medicine.disease Androgen receptor medicine.anatomical_structure Endocrinology Phenotype Receptors Androgen Androgen insensitivity syndrome Prostate surgery Female business |
| Zdroj: | Archives of gynecology and obstetrics. 282(5) |
| ISSN: | 1432-0711 |
| Popis: | Complete androgen insensitivity syndrome (CAIS) is a rare androgen receptor function disorder where phenotypic female has a male genotype. They mostly present as bilateral inguinal hernias containing testes. Uterus and cervix are absent.The authors present a case of CAIS in a 22-year-old female where the presence of testes, prostatic tissue and seminal vesicles was confirmed by ultrasonography, hormonal analysis, operative findings and histopathological study. She was second of the two sisters and her elder sister was also diagnosed with CAIS.High levels of testosterone seen in CAIS can stimulate Wolffian duct development/differentiation. Gonadectomy is advisable in such patients to avoid future neoplastic changes. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|
Full text from SpringerLink