The Relationship Between Otitis Media With Effusion and Gastroesophageal Reflux Disease: A Meta-analysis
| Autor: | Yun Tang, Xiong Chen, Zeng-Hong Wu, Xun Niu, Hai-Ying Sun |
|---|---|
| Rok vydání: | 2020 |
| Předmět: |
Adult
medicine.medical_specialty Funnel plot Subgroup analysis 03 medical and health sciences 0302 clinical medicine Internal medicine Odds Ratio medicine Humans Child 030223 otorhinolaryngology Otitis Media with Effusion business.industry Publication bias Odds ratio medicine.disease Sensory Systems Confidence interval Otitis Media Otitis Otorhinolaryngology Meta-analysis Gastroesophageal Reflux GERD Neurology (clinical) medicine.symptom business 030217 neurology & neurosurgery |
| Zdroj: | Otology & Neurotology. 42:e245-e253 |
| ISSN: | 1537-4505 1531-7129 |
| Popis: | OBJECTIVE Recent studies have investigated the mechanism by which refluxed gastric materials reach the middle ear, to establish otitis media with effusion (OME) causal relation between them in both children and adults. Therefore, the relationship between OME and gastro-esophageal reflux disease (GERD) should be further studied extensively. METHODS To identify eligible original articles, we searched a range of computerized databases, including Medline via PubMed, EMBASE, CNKI, and Web of Science with a systematic searching strategy. Subgroup analysis was performed to analyze heterogeneity and Egger and Begg funnel plot to assess the publication bias of the included articles. RESULTS The meta-analysis had an overall sample size of 1961. We identified a significant relationship between OME and GERD, with a pooled odds ratio (OR) of 4.52 (95% confidence interval [CI]: 2.42-8.44; p |
| Databáze: | OpenAIRE |
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