Varying the heart rate response to dynamic exercise in pacemaker-dependent subjects: effects on cardiac output and cerebral blood velocity
| Autor: | Johannes J. van Lieshout, Lysander W. J. Bogert, Ayten Erol-Yilmaz, Raymond Tukkie |
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| Přispěvatelé: | Other departments, Amsterdam Cardiovascular Sciences, General Internal Medicine |
| Jazyk: | angličtina |
| Rok vydání: | 2005 |
| Předmět: |
Male
medicine.medical_specialty Cardiac output Middle Cerebral Artery Pacemaker Artificial animal diseases Diastole Physical exercise Blood Pressure Heart Rate Internal medicine medicine.artery Heart rate Medicine Humans Cardiac Output Aged Exercise Tolerance business.industry General Medicine Stroke volume Middle Aged Echoencephalography Blood pressure Endocrinology Heart Block Cerebral blood flow Middle cerebral artery Cardiology Electrocardiography Ambulatory Exercise Test Linear Models Female business Blood Flow Velocity |
| Zdroj: | Clinical science (London, England, 109(6), 493-501. Portland Press Ltd. |
| ISSN: | 0143-5221 |
| DOI: | 10.1042/cs20050094 |
| Popis: | Cerebral blood flow increases upon the transition from rest to moderate exercise, but becomes affected when the ability to raise CO (cardiac output) is limited. HR (heart rate) is considered to contribute significantly to the increase in CO in the early stages of dynamic exercise. The aim of the present study was to test whether manipulation of the HR response in patients dependent on permanent rate-responsive ventricular pacing contributes to the increase in CO, MCA Vmean [mean MCA (middle cerebral artery) velocity] and work capacity during exercise. The effect of setting the pacemaker to DSS (‘default’ sensor setting) compared with OSS (‘optimized’ sensor setting) on blood pressure, CO, SV (stroke volume) and MCA Vmean was evaluated during ergometry cycling. From rest to exercise at 75 W, the rise in HR in OSS [from 73 (65–87) to 116 (73–152) beats/min; P |
| Databáze: | OpenAIRE |
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