Association of carotid artery intima-media thickness with complex aortic atherosclerosis in patients with recent stroke
| Autor: | Emmanouil S. Brilakis, Rose Lee Dorn, Panayotis Fasseas, William VanDecker, Marc Cohen, Biana Leybishkis, Nelson M. Wolf, Andrew B. Roberts, Alexis B. Sokil |
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| Rok vydání: | 2002 |
| Předmět: |
Male
medicine.medical_specialty Arteriosclerosis Carotid Artery Common Aorta Thoracic 030204 cardiovascular system & hematology Sensitivity and Specificity Severity of Illness Index Diagnosis Differential 03 medical and health sciences 0302 clinical medicine Predictive Value of Tests Risk Factors medicine.artery medicine Prevalence Thoracic aorta Humans cardiovascular diseases 030212 general & internal medicine Aged Aortic atherosclerosis Aged 80 and over Aorta Aortic Segment Ultrasonography Doppler Duplex business.industry Carotid ultrasonography Middle Aged Pennsylvania medicine.disease Stroke Atheroma Intima-media thickness cardiovascular system Female Radiology Cardiology and Cardiovascular Medicine business Tunica Intima Echocardiography Transesophageal |
| Zdroj: | Scopus-Elsevier |
| ISSN: | 0003-3197 |
| Popis: | This study was undertaken to determine whether carotid intima-media thickness can predict complex aortic atherosclerosis. A retrospective review was conducted of 64 consecutive patients who underwent transesophageal echocardiography and carotid ultrasonography for evaluation of recent ischemic stroke at MCP Hahnemann University, Medical College of Pennsylvania Hospital between January 1, 1999, and December 31, 1999. The mean age was 65 ± 14 years and 59% of the patients were women. Thirty-nine patients (61 %) had carotid atherosclerosis (defined as an intima-media thickness ≥ 1 mm) and seven patients (11%) had complex aortic atherosclerosis (defined as the presence of protruding atheroma ≥4 mm thick, mobile atherosclerotic debris, or plaque ulceration in any aortic segment by transesophageal echocardiography). Compared to patients without complex aortic atherosclerosis, patients with complex aortic atherosclerosis were more likely to have hypercholesterolemia (19% vs 57%, p = 0.05) and a carotid intima-media thickness of 2 mm or greater (35% vs 86%, p = 0.02). A carotid intima-media thickness of 2 mm or more had 86% sensitivity, 65% specificity, 23% positive predictive value, 97% negative predictive value, 2.5 positive likelihood ratio, and 0.22 negative likelihood ratio for the diagnosis of complex aortic atherosclerosis. Carotid intima- media thickness measurement can be used to noninvasively estimate the probability of complex aortic atherosclerosis. A carotid intima-media thickness less than 2 mm makes complex aortic atherosclerosis very unlikely. |
| Databáze: | OpenAIRE |
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