Bowenoid papulosis unveiling a rare cause of immunosuppression

Autor: Betsy Ambooken, Neelakandhan Asokan, Prizey Philip, K T Jisha
Rok vydání: 2019
Předmět:
Adult
Pathology
medicine.medical_specialty
medicine.medical_treatment
Enzyme-Linked Immunosorbent Assay
Dermatology
Virus
Genital warts
Serology
Diagnosis
Differential

03 medical and health sciences
0302 clinical medicine
Retrovirus
immune system diseases
hemic and lymphatic diseases
Antineoplastic Combined Chemotherapy Protocols
Medicine
Humans
Leukemia-Lymphoma
Adult T-Cell

Pharmacology (medical)
030212 general & internal medicine
Cyclophosphamide
Immunosuppression Therapy
Human T-lymphotropic virus 1
030505 public health
biology
business.industry
Public Health
Environmental and Occupational Health

virus diseases
Immunosuppression
biology.organism_classification
medicine.disease
Bowenoid papulosis
Peripheral blood
Infectious Diseases
medicine.anatomical_structure
Treatment Outcome
Condylomata Acuminata
Doxorubicin
Vincristine
Carcinoma
Squamous Cell

Prednisone
Female
Bone marrow
0305 other medical science
business
Precancerous Conditions
Zdroj: International journal of STDAIDS. 30(5)
ISSN: 1758-1052
Popis: Bowenoid papulosis (BP) is a premalignant condition usually caused by oncogenic types of human papillomavirus (HPV) presenting clinically as warty genital papules. Adult T-cell leukaemia–lymphoma (ATLL) is a peripheral T-cell leukaemia–lymphoma caused by the retrovirus, human T-cell lymphotropic virus 1 (HTLV-1). We report a case of BP initially mistaken as genital warts; on detailed evaluation the patient had features of chronic immunosuppression. The presence of leukaemic cells in the peripheral blood, bone marrow and skin along with a positive HTLV-1 serology confirmed the diagnosis of ATLL.
Databáze: OpenAIRE