Pattern of antibiotic prescriptions for outpatients with acute respiratory tract infections in Japan, 2013–15: a retrospective observational study
| Autor: | Kazuaki Shinomiya, Toshiaki Sendo, Hideharu Hagiya, Toshihiro Koyama, Yoshihisa Kitamura, Naoko Mikami, Ayako Ohshima, Yasuhisa Tatebe, Shiro Hinotsu, Ken Tasaka, Mitsunobu R. Kano, Hiroyoshi Y. Tanaka, Yusuke Teratani, Yoshito Zamami, Mayu Adachi |
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| Rok vydání: | 2018 |
| Předmět: |
Adult
Male medicine.medical_specialty medicine.drug_class Cephalosporin Antibiotics Inappropriate Prescribing Young Adult 03 medical and health sciences 0302 clinical medicine Antibiotic resistance Japan Internal medicine Outpatients medicine Humans 030212 general & internal medicine Practice Patterns Physicians' Medical prescription Respiratory Tract Infections Aged Retrospective Studies Respiratory tract infections business.industry 030503 health policy & services Public health Retrospective cohort study Middle Aged Anti-Bacterial Agents Penicillin Female 0305 other medical science Family Practice business Fluoroquinolones medicine.drug |
| Zdroj: | Family Practice. 36:402-409 |
| ISSN: | 1460-2229 |
| DOI: | 10.1093/fampra/cmy094 |
| Popis: | Background In this age of antimicrobial resistance, unnecessary use of antibiotics to treat non-bacterial acute respiratory tract infections (ARTIs) and inappropriate use of antibiotics in treating bacterial ARTIs are public health concerns. Purpose Our aim is to identify the pattern of oral antibiotic prescriptions for outpatients with ARTIs in Japan. Methods We analysed health insurance claims data of patients (aged ≤74 years) from 2013 to 2015, to determine the pattern of antibiotic prescriptions for outpatient ARTIs and calculated the proportion of each antibiotic. Results Data on 4.6 million antibiotic prescriptions among 1559394 outpatients with ARTIs were analysed. The most commonly prescribed classes of antibiotics included cephalosporins (41.9%), macrolides (32.8%) and fluoroquinolones (14.7%). The proportion of first-, second- and third-generation cephalosporins was 1.0%, 1.7% and 97.3%, respectively. Fluoroquinolones accounted for a quarter of the prescriptions for ARTIs in patients aged >20 years. In contrast, penicillins accounted for just 8.0% of the total number of antibiotic prescriptions for ARTIs. Conclusions According to clinical guidelines, penicillins are first-line antibiotics against ARTIs. However, third-generation cephalosporins, macrolides and fluoroquinolones are more frequently prescribed in Japan. Although we could not assess the extent to which appropriate antibiotics are selected, our results support the necessity of improving antibiotic choices in the treatment of ARTIs. |
| Databáze: | OpenAIRE |
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