Effect of pimobendan on left atrial function: an echocardiographic pilot study in 11 healthy cats
Autor: | M. Baron Toaldo, M. Pollesel, Alessia Diana |
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Přispěvatelé: | University of Zurich, Baron Toaldo, Marco, Baron Toaldo M., Pollesel M., Diana A. |
Rok vydání: | 2020 |
Předmět: |
Male
medicine.medical_specialty 10253 Department of Small Animals Physiology 3400 General Veterinary Cardiomyopathy Pilot Projects Contractility Placebo group Ventricular Function Left Feline Heart Rate Left atrial Internal medicine Animals Medicine Heart Atria CATS 630 Agriculture General Veterinary Ventricular function business.industry 1314 Physiology Fractional shortening medicine.disease Hypertrophic cardiomyopathy Pyridazines Atrium Pimobendan Pulmonary Veins Echocardiography Cats Cardiology 570 Life sciences biology Atrial Function Left Female business Blood Flow Velocity medicine.drug |
Zdroj: | Journal of Veterinary Cardiology. 28:37-47 |
ISSN: | 1760-2734 |
Popis: | Objectives: – To evaluate the effect of a single dose of pimobendan on left atrial (LA) function in healthy cats. Animals: – Eleven client owned healthy cats. Material and methods: – Standardized and repeated echocardiographic examinations were performed on healthy and conscious cats before and after a single dose of orally administered pimobendan (1.25 mg/cat). Left atrial systolic functional parameters were assessed. Results: – Some of the tested parameters of LA function showed significant improvement after pimobendan administration, whereas no significant effect on left ventricular function was observed. In particular, LA minimal diameters obtained from M-mode images in short (p=0.018) and long (p=0.009) axis reduced after pimobendan administration, whereas LA fractional shortening from short (p=0.027) and long (p=0.042) axis and LA appendage emptying velocity (p |
Databáze: | OpenAIRE |
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