The effect of frankincense (Boswellia serrata, oleoresin) and ginger (Zingiber officinale, rhizoma) on heavy menstrual bleeding: A randomized, placebo-controlled, clinical trial
| Autor: | Mohammad Mazaheri, Mahmoud Babaeian, Awat Feizi, Mustafa Ghanadian, Safoura Rouholamin, Razieh Eshaghian |
|---|---|
| Rok vydání: | 2019 |
| Předmět: |
Adult
Complementary and Manual Therapy medicine.medical_specialty media_common.quotation_subject Ibuprofen Ginger Placebo 03 medical and health sciences 0302 clinical medicine Double-Blind Method Internal medicine medicine Humans Outpatient clinic Boswellia 030212 general & internal medicine Menorrhagia Menstrual cycle media_common Advanced and Specialized Nursing biology Plant Extracts business.industry Frankincense biology.organism_classification Clinical trial Complementary and alternative medicine Quality of Life Boswellia serrata Female Zingiber officinale Plant Preparations business Rhizome 030217 neurology & neurosurgery medicine.drug |
| Zdroj: | Complementary Therapies in Medicine. 42:42-47 |
| ISSN: | 0965-2299 |
| DOI: | 10.1016/j.ctim.2018.09.022 |
| Popis: | To evaluate the effect of frankincense (Boswellia serrata, oleoresin) and ginger (Zingiber officinale, rhizoma) as complementary treatments for heavy menstrual bleeding (HMB) among women of reproductive age.Randomized, placebo-controlled, clinical trial.Gynecology outpatient clinics.Patients with HMB (n = 102) were randomly assigned to three groups. All patients received ibuprofen (200 mg) and either frankincense (300 mg), ginger (300 mg), or a placebo, which contains 200 mg anhydrous lactose as the filling agent and was similar in appearance to the two other drugs. Patients received the medications three times a day for seven days of the menstrual cycle, starting from the first bleeding day and this was repeated for two consecutive menstrual cycles.Amount and duration of menstrual bleeding and quality of life (QOL).Duration of menstrual bleeding was decreased in the frankincense (-1.77 ± 2.47 days, P = 0.003) and ginger (-1.8 ± 1.79 days, P = 0.001) groups, but not in the placebo group (-0.52 ± 1.86 days, P = 0.42). Amount of menstrual bleeding was decreased in all (P 0.05), with no difference among the study groups (P 0.05). More improvement in QOL was observed in the frankincense (-25.7 ± 3.1; P 0.001) and ginger (-29.2 ± 3.7: P 0.001) groups compared to the placebo group (-15.07 ± 3.52; P 0.001) and between the groups, differences were statistically significant (P = 0.02).Ginger and frankincense seem to be effective complementary treatments for HMB. Further studies with a larger sample size and longer follow-up are warranted in this regard. |
| Databáze: | OpenAIRE |
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