Factors Affecting Patency of In Situ Saphenous Vein Bypass: Two Year Results from LIMBSAVE (Treatment of critical Limb Ischaemia with infragenicular Bypass adopting in situ SAphenous VEin technique) Registry

Autor: Nicola Troisi, Daniele Adami, Stefano Michelagnoli, Raffaella Berchiolli, Federico Accrocca, Alessio Amico, Andrea Angelini, Luca Arnuzzo, Andrea Ascoli Marchetti, Luca Attisani, Gennaro Bafile, Giuseppe Baldino, Enrico Barbanti, Stefano Bartoli, Raffaello Bellosta, Filippo Benedetto, Raoul Borioni, Franco Briolini, Cristina Busoni, Stefano Camparini, Pierluigi Cappiello, Luciano Carbonari, Francesco Casella, Giovanni Celoria, Andrea Chiama, Emiliano Chisci, Efrem Civilini, Francesco Codispoti, Barbara Conti, Giovanni Coppi, Giovanni De Blasis, Marcello D’Elia, Rossella Di Domenico, Carla Di Girolamo, Leonardo Ercolini, Alessandra Ferrari, Mauro Ferrari, Enzo Forliti, Paolo Frigatti, Dalmazio Frigerio, Pierfrancesco Frosini, Luca Garriboli, Antonio Nicola Giordano, Walter Guerrieri, Antonio Jannello, Mafalda Massara, Maurizio Merlo, Roberto Mezzetti, Tommaso Miccoli, Domenico Milite, Pietro Mingazzini, Marina Muncinelli, Giovanni Nano, Marco Natola, Claudio Novali, Giancarlo Palasciano, Reinhold Perkmann, Federica Persi, David Petruccelli, Mauro Pinelli, Giorgio Poletto, Carla Porta, Carlo Pratesi, Gianguido Pruner, Giovanni Ragazzi, Paolo Righini, Mauro Salvini, Paolo Scovazzi, Carlo Setacci, Alberto Maria Settembrini, Andrea Siani, Roberto Silingardi, Antonino Silvestro, Francesco Talarico, Valerio Tolva, Antonio Trani, Santi Trimarchi, Yamume Tshomba, Gennaro Vigliotti, Daniela Viola, Pietro Volpe, Federico Zani
Rok vydání: 2021
Předmět:
Zdroj: European journal of vascular and endovascular surgery : the official journal of the European Society for Vascular Surgery. 64(4)
ISSN: 1532-2165
Popis: The aim was to demonstrate contemporary outcomes of in situ saphenous vein bypass using a valvulotome.Analysis of two year outcomes of a multicentre registry based on the treatment of critical Limb Ischaemia with infragenicular Bypass adopting in situ SAphenous VEin technique (LIMBSAVE). Between January 2018 and December 2019, 541 patients in 43 centres were enrolled. In all patients an innovative valvulotome was used. Early outcomes were assessed. Two year outcomes according to Kaplan-Meier curves in terms of patency and limb salvage were evaluated. Associations between patient and procedure variables were analysed with univariable and multivariable analyses.In all cases, a valvulotome was able to lyse the valves. Vein injury due to the in situ technique was 3.5%. Thirty day mortality and major amputation rates were 3% and 0.9%, respectively. Mean follow up was 12.1 months. Two year estimated primary patency, primary assisted patency, secondary patency, and limb salvage were 69.1%, 81.4%, 86.5%, and 94.5%, respectively. Multivariable analysis showed an association between pre-operative vein diameter3 mm and lower primary patency (hazard ration [HR] 14.3, p.001), primary assisted patency (HR 9.4, p = .002), secondary patency (HR 7.2, p = .007), and limb salvage (HR 7.8, p = .005) rates. Distal anastomosis to a tibial or foot vessel was also associated with lower primary patency (HR 4.8, p = .033), and primary assisted patency (HR 6, p = .011) rates. Use of a suprafascial tributary collateral as a graft was associated with lower primary patency (HR 6.7, p = .013), and primary assisted patency (HR 4.2, p = .042) rates.Vein diameter3 mm, distal anastomosis on a tibial or foot vessel, and use of a suprafascial tributary collateral as a graft were significantly associated with loss of patency and limb loss during follow up.
Databáze: OpenAIRE
Externí odkaz: