Requirement of the agr Locus for Colony Spreading of Staphylococcus aureus

Autor:	Girbe Buist, Mark J. J. B. Sibbald, Annette Dreisbach, Emma L. Denham, Jaap Willem Back, Eleni Tsompanidou, Monika A. Chlebowicz, Jan Maarten van Dijl
Přispěvatelé:	University of Groningen, Translational Immunology Groningen (TRIGR)
Jazyk:	angličtina
Rok vydání:	2011
Předmět:	Staphylococcus aureus Micrococcaceae VIRULENCE-DETERMINANT EXPRESSION Physiology and Metabolism Virulence Motility SIGNAL-TRANSDUCTION Human pathogen Locus (genetics) medicine.disease_cause Microbiology Surface-Active Agents Bacterial Proteins NUCLEOTIDE-SEQUENCE medicine REGULATOR AGR Molecular Biology IN-VIVO GENE-EXPRESSION Genetics CHROMOSOME MEC SCCMEC biology food and beverages Quorum Sensing GENOME SEQUENCE Gene Expression Regulation Bacterial biochemical phenomena metabolism and nutrition biology.organism_classification DELTA-HEMOLYSIN Quorum sensing PHENOL-SOLUBLE MODULINS Mutation Trans-Activators bacteria Bacteria
Zdroj:	Journal of Bacteriology, 193(5), 1267-1272. AMER SOC MICROBIOLOGY
ISSN:	0021-9193
Popis:	The important human pathogen Staphylococcus aureus is known to spread on soft agar plates. Here, we show that colony spreading of S. aureus involves the agr quorum-sensing system. This finding can be related to the agr -dependent expression of biosurfactants, such as phenol-soluble modulins, suggesting a connection between spreading motility and virulence.
Databáze:	OpenAIRE
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