Addressing the inter-individual variation in response to consumption of plant food bioactives: Towards a better understanding of their role in healthy aging and cardiometabolic risk reduction

Autor: Tom Van de Wiele, Eileen R. Gibney, Francisco A. Tomás-Barberán, Rikard Landberg, Dragan Milenkovic, Maria Theresa Garcia-Conesa, Ana Rodriguez-Mateos, Baukje de Roos, Marina Heinonen, Christine Morand, Claudine Manach
Přispěvatelé: European Cooperation in Science and Technology, European Commission, Unité de Nutrition Humaine (UNH), Institut National de la Recherche Agronomique (INRA)-Université Clermont Auvergne [2017-2020] (UCA [2017-2020]), Center for Microbial Ecology and Technology (CMET), Universiteit Gent = Ghent University [Belgium] (UGENT), Division of Cardiology, Pulmonology and Vascular Medicine, University Hospital Düsseldorf, Rowett Institute of Nutrition and Health, University of Aberdeen, Centro de Edafologia y Biologia Aplicada del Segura, Department of Food Science, Cornelle University, Nutritional Epidemiology Unit, Fondazione IRCCS Istituto Nazionale Tumori - National Cancer Institute [Milan], Institute of Food and Health, University College Dublin [Dublin] (UCD), Department of Food and Environmental Sciences, Food Chemistry, University of Helsinki, COST (European Cooperation in Science and Technology):FA1403 POSITIVe, Unité de Nutrition Humaine - Clermont Auvergne (UNH), Institut National de la Recherche Agronomique (INRA)-Université Clermont Auvergne (UCA), Ghent University [Belgium] (UGENT), Universiteit Gent = Ghent University (UGENT), Helsingin yliopisto = Helsingfors universitet = University of Helsinki
Rok vydání: 2017
Předmět:
Agriculture and Food Sciences
0301 basic medicine
and promotion of well-being
biological responsiveness
Health Behavior
Phytochemicals
VEGETABLE CONSUMPTION
Review
bioavailability and metabolism
BLOOD MONONUCLEAR-CELLS
Inter‐individual variation
Cardiovascular
Plant foods
nutrition préventive
Oral and gastrointestinal
Inter-individual variation
Healthy Aging
Risk Factors
cardiovascular disease
GENETIC-VARIANTS
maladie cardiovasculaire
Biological responsiveness
Randomized Controlled Trials as Topic
2. Zero hunger
Cardiometabolic risk
Nutrition and Dietetics
Cardiometabolic health
RANDOMIZED CONTROLLED-TRIAL
Plants
3. Good health
Stroke
Variation (linguistics)
POSTMENOPAUSAL WOMEN
CARDIOVASCULAR-DISEASE
Cardiovascular Diseases
plant food bioactives
Public Health and Health Services
CORONARY-ARTERY-DISEASE
Diet
Healthy
Plants
Edible
variabilité inter individuelle
Biotechnology
cardiometabolic health
Bioavailability and metabolism
education
Reviews
HEART-DISEASE
Biology
Affect (psychology)
03 medical and health sciences
Edible
Food Sciences
Metabolic Diseases
Environmental health
inter-individual variation
Humans
Obesity
Healthy aging
3.3 Nutrition and chemoprevention
Metabolic and endocrine
Nutrition
INTERVENTION TRIAL
Consumption (economics)
Healthy
030109 nutrition & dietetics
Nutrition & Dietetics
business.industry
Prevention
PRODUCER PHENOTYPE
Prevention of disease and conditions
Diet
Review article
Good Health and Well Being
alimentation végétale
Plant food bioactives
Position paper
business
Risk Reduction Behavior
[SDV.AEN]Life Sciences [q-bio]/Food and Nutrition
[SDV.MHEP]Life Sciences [q-bio]/Human health and pathology
Food Science
Zdroj: Digital.CSIC. Repositorio Institucional del CSIC
instname
Molecular Nutrition and Food Research
Molecular Nutrition and Food Research, Wiley-VCH Verlag, 2017, 61 (6), pp.1-16. ⟨10.1002/mnfr.201600557⟩
Molecular Nutrition and Food Research, 2017, 61 (6), pp.1-16. ⟨10.1002/mnfr.201600557⟩
Molecular nutrition & food research, vol 61, iss 6
Molecular Nutrition & Food Research
MOLECULAR NUTRITION & FOOD RESEARCH
ISSN: 1613-4125
1613-4133
DOI: 10.1002/mnfr.201600557⟩
Popis: Bioactive compounds in plant-based foods have health properties that contribute to the prevention of age-related chronic diseases, particularly cardiometabolic disorders. Conclusive proof and understanding of these benefits in humans is essential in order to provide effective dietary recommendations but, so far, the evidence obtained from human intervention trials is limited and contradictory. This is partly due to differences between individuals in the absorption, distribution, metabolism and excretion of bioactive compounds, as well as to heterogeneity in their biological response regarding cardiometabolic health outcomes. Identifying the main factors underlying inter-individual differences, as well as developing new and innovative methodologies to account for such variability constitute an overarching goal to ultimately optimize the beneficial health effects of plant food bioactives for each and every one of us. In this respect, this position paper from the COST Action FA1403-POSITIVe examines the main factors likely to affect the individual responses to consumption of plant food bioactives and presents perspectives for assessment and consideration of inter-individual variability.
The authors would like to acknowledge networking support by the COST Action FA 1403 POSITIVe (Inter-individual variation in response to consumption of plant food bioactives and determinants involved), supported by COST (European Cooperation in Science and Technology).
Databáze: OpenAIRE
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