A systematically collated library of prescribing safety indicators for people with chronic kidney disease
| Autor: | Fergus Caskey, George Kimpton, Christine Sluman, Sam J L Hayward, Fiona Smith, Barnaby Hole, Penny Whiting |
|---|---|
| Rok vydání: | 2020 |
| Předmět: |
medicine.medical_specialty
Population Prescribing safety indicators Inappropriate Prescribing urologic and male genital diseases lcsh:RC870-923 primary care population Anatomical therapeutic chemical Internal medicine Chronic kidney disease medicine Outpatient setting CKD Humans Multiple Chronic Conditions prescribing safely Renal Insufficiency Chronic education potentially inappropriate prescribing Polypharmacy Safety indicators education.field_of_study prescribing safety indicators business.industry Potentially inappropriate prescribing Contraindications Drug medicine.disease lcsh:Diseases of the genitourinary system. Urology Increased risk Nephrology Emergency medicine Prescribing safety outpatient setting Primary care population business chronic kidney disease Kidney disease Systematic search Research Article |
| Zdroj: | BMC Nephrology BMC Nephrology, Vol 21, Iss 1, Pp 1-7 (2020) Smith, F, Hayward, S J L, Hole, B, Kimpton, G J, Sluman, C, Whiting, P F & Caskey, F J 2020, ' A systematically collated library of prescribing safety indicators for people with chronic kidney disease ', BMC Nephrology, vol. 21, 493 (2020) . https://doi.org/10.1186/s12882-020-02158-0 |
| DOI: | 10.21203/rs.3.rs-41396/v3 |
| Popis: | Background People with chronic kidney disease (CKD) have high levels of co-morbidity and polypharmacy placing them at increased risk of prescribing-related harm. Tools for assessing prescribing safety in the general population using prescribing safety indicators (PSIs) have been established. However, people with CKD pose different prescribing challenges to people without kidney disease. Therefore, PSIs designed for use in the general population may not include all PSIs relevant to a CKD population. The aim of this study was to systematically collate a library of PSIs relevant to people with CKD. Methods A systematic literature search identified papers reporting PSIs. CKD-specific PSIs were extracted and categorised by Anatomical Therapeutic Chemical (ATC) classification codes. Duplicate PSIs were removed to create a final list of CKD-specific PSIs. Results Nine thousand, eight hundred fifty-two papers were identified by the systematic literature search, of which 511 proceeded to full text screening and 196 papers were identified as reporting PSIs. Following categorisation by ATC code and duplicate removal, 841 unique PSIs formed the final set of CKD-specific PSIs. The five ATC drug classes containing the largest proportion of CKD-specific PSIs were: Cardiovascular system (26%); Nervous system (13.4%); Blood and blood forming organs (12.4%); Alimentary and metabolism (12%); and Anti-infectives for systemic use (11.3%). Conclusion CKD-specific PSIs could be used alone or alongside general PSIs to assess the safety and quality of prescribing within a CKD population. |
| Databáze: | OpenAIRE |
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