A double-blind comparison of topical therapy of chlamydial ocular infection (TRIC infection) with rifampicin or chlortetracycline
| Autor: | S Darougar, P. A. Hunter, H. El-Sheikh, N D Viswalingam, P. Yearsley |
|---|---|
| Rok vydání: | 1981 |
| Předmět: |
Adult
Male Chlortetracycline medicine.medical_specialty Adolescent Administration Topical Keratoconjunctivitis Chlamydia trachomatis medicine.disease_cause Gastroenterology Double blind Random Allocation Cellular and Molecular Neuroscience Double-Blind Method Internal medicine medicine Humans In patient Trachoma Clinical Trials as Topic business.industry Chlamydia Infections Conjunctivitis Inclusion Middle Aged medicine.disease eye diseases Sensory Systems Surgery Ophthalmology Positive culture Female Rifampin business Rifampicin Research Article medicine.drug |
| Zdroj: | British Journal of Ophthalmology. 65:549-552 |
| ISSN: | 0007-1161 |
| DOI: | 10.1136/bjo.65.8.549 |
| Popis: | A double-blind stratified trial was carried out on 85 patients to assess the efficacy of topical therapy with 1% chlortetracycline eye ointment in comparison with 1% rifampicin eye ointment in the treatment of chlamydial ocular infection of sexually transmitted origin (paratrachoma). Patients included were selected on the basis of positive culture for Chlamydia trachomatis. A 6-week course of treatment with chlortetracycline or rifampicin 3 times daily gave a clinical cure rate of 80% and 75% and a microbiological cure rate of 93% and 86% respectively. In patients who were not cured the intensity of inflammatory responses was considerably reduced. |
| Databáze: | OpenAIRE |
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