Activation of intrinsic laryngeal muscles during cough
| Autor: | F. B. Sant'Ambrogio, Giuseppe Sant'Ambrogio, Samuel T. Kuna, C R Vanoye |
|---|---|
| Rok vydání: | 1997 |
| Předmět: |
Pulmonary and Respiratory Medicine
medicine.diagnostic_test Electromyography business.industry Respiratory disease Stimulation Anatomy respiratory system Critical Care and Intensive Care Medicine medicine.disease respiratory tract diseases Diaphragm (structural system) Superior laryngeal nerve Dogs Cough Anesthesia Laryngeal Muscle Animals Medicine Laryngeal Muscles business Airway Glottic narrowing |
| Zdroj: | American Journal of Respiratory and Critical Care Medicine. 155:637-641 |
| ISSN: | 1535-4970 1073-449X |
| DOI: | 10.1164/ajrccm.155.2.9032206 |
| Popis: | We studied the pattern of discharge of the posterior cricoarytenoid (PCA), cricothyroid (CT), thyroarytenoid (TA), and arytenoideus transversus (AR) muscles during cough in 12 anesthetized dogs. Diaphragm electromyographic (EMG) activity was also recorded, together with subglottic and esophageal pressures. Trains of repetitive coughs were induced by mechanically stimulating the tracheobronchial airway. Trials with the upper airway isolated from and connected to the lower airway were performed before and following bilateral sectioning of the internal branch of the superior laryngeal nerve (SLN). The immediate effect of tracheal stimulation was an "apneic" period at FRC, during which the PCA, a laryngeal abductor, showed a progressive increase in activity accompanied by small, variable increases in the activity of the CT and the laryngeal adductors, the TA and AR. The subsequent cough efforts were divided into three phases: inspiration, glottic narrowing, and forced expiration. PCA activity was greatest during the inspiratory phase and CT activity was greatest during the expiratory phase. Peak subglottic pressure occurred during glottic narrowing and coincided with the greatest activation of the TA and AR during the cough effort, and suppression of the PCA and CT. The patterns of EMG activation were not affected by the route of breathing or SLN section. The results suggest the presence of a uniquely central process controlling laryngeal muscles during cough, independent of laryngeal sensory feedback. |
| Databáze: | OpenAIRE |
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