Nanostructured nickel oxide electrodes for non-enzymatic electrochemical glucose sensing
| Autor: | Aliesha D. Johnson, Natasha Singer, Rajesh G Pillai, Abebaw B Jemere, Kenneth D. M. Harris |
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| Jazyk: | angličtina |
| Rok vydání: | 2020 |
| Předmět: |
Blood Glucose
Materials science Surface Properties education chemistry.chemical_element 02 engineering and technology Biosensing Techniques 010402 general chemistry Electrochemistry 01 natural sciences Analytical Chemistry Nickel amperometry Humans Particle Size Electrodes glancing angle deposition (glad) Nickel oxide Glucose Measurement Electrochemical Techniques 021001 nanoscience & nanotechnology Ascorbic acid Amperometry 0104 chemical sciences Nanostructures chemistry Electrode Cyclic voltammetry nanostructured electrodes 0210 nano-technology Nuclear chemistry non-enzymatic sensors |
| Popis: | Nanostructured nickel (Ni) and nickel oxide (NiO) electrodes were fabricated on Ni foils using the glancing angle deposition (GLAD) technique. Cyclic voltammetry and amperometry showed the electrodes enable non-enzymatic electrochemical determination of glucose in strongly alkaline media. Under optimized conditions of NaOH concentration and working potential (~ 0.50 V vs. Ag/AgCl), the GLAD electrodes performed far better than bare Ni foil electrodes, with the GLAD NiO electrode showing an outstanding sensitivity (4400 μA mM−1 cm−2), superior detection limit (7 nM), and wide dynamic range (0.5 μM–9 mM), with desirable selectivity and reproducibility. Based on their performance at a low concentration, the GLAD NiO electrodes were also used to quantify glucose in artificial urine and sweat samples which have significantly lower glucose levels than blood. The GLAD NiO electrodes showed negligible response to the common interferents in glucose measurement (uric acid, dopamine, serotonin, and ascorbic acid), and they were not poisoned by high amounts of sodium chloride. |
| Databáze: | OpenAIRE |
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