Peripheral arterial disease, type 2 diabetes and postprandial lipidaemia: Is there a link?
| Autor: | José Ramírez-Bollero, Carmen Pérez-López, Pedro Valdivielso |
|---|---|
| Přispěvatelé: | UGC de Medicina Interna, Hospital Virgen de la Victoria de Málaga, Departamento de Medicina y Dermatología, Universidad de Málaga, Spain., Grant to Grupo CTS-159 of PAIDI (Plan Andaluz de Investigación, Desarrollo e Innovación) de la Junta de Andalucía |
| Rok vydání: | 2014 |
| Předmět: |
medicine.medical_specialty
Anklebrachial index Apolipoprotein B Endocrinology Diabetes and Metabolism Chemicals and Drugs::Lipids::Lipoproteins::Lipoproteins HDL::Cholesterol HDL [Medical Subject Headings] Ischemia Apolipoproteína B-48 Type 2 diabetes Triglicéridos Chemicals and Drugs::Carbohydrates::Glycosides::Hemoglobin A Glycosylated [Medical Subject Headings] Internal medicine Diabetes mellitus Peripheral arterial disease Postprandial lipidaemia Internal Medicine Medicine Topic Highlight Non-fasting triglycerides Enfermedad arterial periférica Chemicals and Drugs::Lipids::Glycerides::Triglycerides [Medical Subject Headings] LDL-Colesterol biology business.industry Índice tobillo braquial Type 2 Diabetes Mellitus Chemicals and Drugs::Lipids::Lipoproteins::Lipoproteins LDL::Cholesterol LDL [Medical Subject Headings] medicine.disease Intermittent claudication Arteriosclerotic Cardiovascular Disease HDL-Colesterol Diabetes mellitus tipo 2 Endocrinology Postprandial Diseases::Nutritional and Metabolic Diseases::Metabolic Diseases::Lipid Metabolism Disorders::Dyslipidemias::Hyperlipidemias [Medical Subject Headings] biology.protein Cardiology Diseases::Nutritional and Metabolic Diseases::Metabolic Diseases::Glucose Metabolism Disorders::Diabetes Mellitus::Diabetes Mellitus Type 2 [Medical Subject Headings] Analytical Diagnostic and Therapeutic Techniques and Equipment::Diagnosis::Prognosis [Medical Subject Headings] Hemoglobina A Glucosilada medicine.symptom Apolipoprotein B-48 Hiperlipidemias business |
| Zdroj: | World Journal of Diabetes. 5:577 |
| ISSN: | 1948-9358 |
| Popis: | Peripheral arterial disease, manifested as intermittent claudication or critical ischaemia, or identified by an ankle/brachial index < 0.9, is present in at least one in every four patients with type 2 diabetes mellitus. Several reasons exist for peripheral arterial disease in diabetes. In addition to hyperglycaemia, smoking and hypertension, the dyslipidaemia that accompanies type 2 diabetes and is characterised by increased triglyceride levels and reduced high-density lipoprotein cholesterol concentrations also seems to contribute to this association. Recent years have witnessed an increased interest in postprandial lipidaemia, as a result of various prospective studies showing that non-fasting triglycerides predict the onset of arteriosclerotic cardiovascular disease better than fasting measurements do. Additionally, the use of certain specific postprandial particle markers, such as apolipoprotein B-48, makes it easier and more simple to approach the postprandial phenomenon. Despite this, only a few studies have evaluated the role of postprandial triglycerides in the development of peripheral arterial disease and type 2 diabetes. The purpose of this review is to examine the epidemiology and risk factors of peripheral arterial disease in type 2 diabetes, focusing on the role of postprandial triglycerides and particles. Yes |
| Databáze: | OpenAIRE |
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