Relations among clinical scales in schizophrenia
| Autor: | R. C. Gur, Susan M. Resnick, P D Mozley, Roland J. Erwin, Andrew J. Saykin, Stephen E. Levick, Raquel E. Gur |
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| Rok vydání: | 1991 |
| Předmět: |
Psychiatric Status Rating Scales
medicine.medical_specialty Psychosis Psychometrics Thought disorder Combined use Mixed type medicine.disease Psychiatry and Mental health mental disorders Brief Psychiatric Rating Scale Inclusion and exclusion criteria Schizophrenia medicine Cluster Analysis Humans Schizophrenic Psychology medicine.symptom Psychiatry Psychology Scale for the Assessment of Negative Symptoms Clinical psychology |
| Zdroj: | American Journal of Psychiatry. 148:472-478 |
| ISSN: | 1535-7228 0002-953X |
| DOI: | 10.1176/ajp.148.4.472 |
| Popis: | Objective Clinical scales have become established as tools to quantify phenomenological features of schizophrenia. The goal of this study was to examine relations among the following: the Brief Psychiatric Rating Scale (BPRS), the Scale for the Assessment of Positive Symptoms, the Scale for the Assessment of Negative Symptoms, and the deficit-nondeficit classification. Method Forty-seven patients with schizophrenia were recruited according to specific inclusion and exclusion criteria. The standardized assessment procedures were administered by a trained psychiatric research team. Results Examination of the BPRS showed that the patients had highest scores on the thought disorder factor and the symptoms specific to schizophrenia. Classification of patients as having the positive, negative, or mixed type of schizophrenia resulted in a finding of seven with the positive, seven with the negative, and 33 with the mixed type. The division of patients into those with the deficit syndrome (N = 29) and those without (N = 18) was related to symptom specificity and to positive and negative symptoms. Deficit syndrome patients had more symptoms specific to schizophrenia, fewer nonspecific symptoms, and, as expected, greater severity of negative symptoms. Cluster analysis revealed three clusters of patients: those with low negative symptom scores and high scores on specific symptoms (the majority were without the deficit syndrome); those with high scores on negative, positive, and specific symptoms (the majority had the deficit syndrome); and those with lower scores on specific symptoms and high scores on negative and positive symptoms (the majority had the deficit syndrome). Conclusions The scales showed some overlap but also seemed to measure complementary aspects of the phenomenology of schizophrenia. Subtypes of patients identified by the combined use of these scales may differ in underlying pathology. |
| Databáze: | OpenAIRE |
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