Validation of the mainland Chinese version of the inflammatory bowel disease questionnaire (IBDQ) for ulcerative colitis and Crohnʼs disease
Autor: | E J Irvine, Y X Zhou, Yan Chen, W H Ren, M Lai |
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Rok vydání: | 2007 |
Předmět: |
Adult
Male Mainland China China medicine.medical_specialty Adolescent Intraclass correlation Disease Inflammatory bowel disease Crohn Disease Quality of life Sickness Impact Profile Surveys and Questionnaires Internal medicine medicine Humans Immunology and Allergy Colitis Aged Observer Variation Crohn's disease business.industry Gastroenterology Reproducibility of Results Middle Aged medicine.disease Ulcerative colitis digestive system diseases Quality of Life Physical therapy Colitis Ulcerative Female business |
Zdroj: | Inflammatory Bowel Diseases. 13:903-910 |
ISSN: | 1078-0998 |
Popis: | Background/Aims Inflammatory bowel disease affects the quality of a patient’s life in many ways, but no validated instrument for measuring disease-specific quality of life in these patients is available for use in Mainland China. The aim of our study is to develop and validate the Mainland Chinese translation of the Inflammatory Bowel Disease Questionnaire for ulcerative colitis and Crohn’s disease, by assessing its construct validity, discriminant ability, reliability and sensitivity to change. Methods We administered a developed Mainland Chinese version of the Inflammatory Bowel Disease Questionnaire. Ninety-two Mainland Chinese patients (52 with ulcerative colitis and 40 with Crohn’s disease) completed the Mainland Chinese version of the Inflammatory Bowel Disease Questionnaire, the Chinese version of SF-36 and the global scale for general well-being. A subgroup of 71 patients also completed the Mainland Chinese version of the Inflammatory Bowel Disease Questionnaire and the global scales for general well-being on a second occasion. Clinical activity was assessed by the Walmsley and Harvey-Bradshaw simple indices. Results The Mainland Chinese Inflammatory Bowel Disease Questionnaire scores correlated well with the related SF-36 dimensional scores for all four domains (r=0.51-0.82), SF-36 total scores (r=0.58-0.87), the colitis activity index (r=-0.56-0.74), and the Crohn’s disease activity index (r=-0.64-0.78) as well as with the global scales. The Mainland Chinese Inflammatory Bowel Disease Questionnaire was able to discriminate between active and inactive disease. Cronbach’s α was 0.95 in ulcerative colitis and 0.94 in Crohn’s disease. Test-re-test reliability was excellent (intraclass correlation coefficient 0.69-0.93) when it was repeated in patients whose clinical activity index was stable. In contrast, there was a significant difference between the baseline and follow-up measurements in patients whose clinical activity index was changed. Conclusions The Mainland Chinese Inflammatory Bowel Disease Questionnaire proved to be a valid, discriminative and reliable instrument for assessing health-related quality of life in patients with ulcerative colitis and Crohn’s disease in Mainland China. |
Databáze: | OpenAIRE |
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