227 Early detection of systolic and diastolic dysfunction in asymptomatic hypertrophic cardiomyopathy mutation carriers using cardiac magnetic resonance imaging

Autor: Marieke D. Spreeuwenberg, Arthur A.M. Wilde, J. Tim Marcus, Iris K. Rüssel, Tjeerd Germans, Marco J.W. Götte, Albert C. van Rossum, Yigal M. Pinto, Pieter A. Doevendans
Rok vydání: 2008
Předmět:
Zdroj: Journal of Cardiovascular Magnetic Resonance, Vol 10, Iss Suppl 1, p A88 (2008)
ISSN: 1532-429X
DOI: 10.1186/1532-429x-10-s1-a88
Popis: Background Hypertrophic Cardiomyopathy (HCM) is characterized by asymmetric hypertrophy of the left ventricle (LV). While over 400 HCM mutations have been identified, increasing number of HCM mutation carriers without hypertrophy have been detected. No data on regional functional and structural abnormalities in HCM mutation carriers before the development of hypertrophy are yet available. With cardiac magnetic resonance imaging (CMR), both regional function and structure can accurately be evaluated.
Databáze: OpenAIRE