Efficacy of BCG vaccine and Mitomycin C for the treatment of ocular squamous cell carcinoma in bovines
| Autor: | Rani Prameela Devalam, Suresh Kumar Rayadurgam Venkata, Veena Podarala, M. Prasanna Lakshmi |
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| Rok vydání: | 2020 |
| Předmět: |
Male
medicine.medical_specialty Mitomycin Group ii Cattle Diseases Gastroenterology Internal medicine medicine Animals Humans Neoplasm Basal cell Prospective Studies Alternate weeks Nucleic Acid Synthesis Inhibitors Antibiotics Antineoplastic General Veterinary business.industry Eye Neoplasms Mitomycin C Cancer medicine.disease Combined Modality Therapy eye diseases Administration Intravesical medicine.anatomical_structure Urinary Bladder Neoplasms BCG Vaccine Carcinoma Squamous Cell Cattle Female sense organs Eyelid business BCG vaccine |
| Zdroj: | Research in Veterinary Science. 133:48-52 |
| ISSN: | 0034-5288 |
| DOI: | 10.1016/j.rvsc.2020.08.008 |
| Popis: | Bovine ocular squamous cell carcinoma (BOSCC) also called cancer eye, represents the most economically important neoplasm in large animals. Hereditary factors, environmental factors, lack of eyelid pigmentation, age and dietary habits have all been reported to play a role in the etiopathogenesis of bovine ocular squamous cell carcinoma. In group I, six animals with small, localized eye cancer where vision was not affected were included and subjected to intralesional injection of Bacillus Calmette- Guerin (BCG) vaccine at 0, 14, 35, and 56 days interval. In group II (six animals), surgical excision and Mitomycin C 0.04% topically on alternate weeks for two months as adjunctive therapy. All the animals recovered completely with no recurrence for a follow up period of one year. |
| Databáze: | OpenAIRE |
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