Pain sensitivity does not differ between obese and healthy weight individuals
| Autor: | James Peugh, Nichole M. Emerson, Robert C. Coghill, Hadas Nahman-Averbuch |
|---|---|
| Rok vydání: | 2021 |
| Předmět: |
medicine.medical_specialty
General Section Quantitative sensory testing Audiology Impulsivity Heat pain Quality of life Anesthesiology Noxious stimulus Medicine RD78.3-87.3 Obesity Healthy controls business.industry Chronic pain medicine.disease Cold pain Anesthesiology and Pain Medicine Nociception Anxiety medicine.symptom business Tolerance Body mass index Research Paper |
| Zdroj: | Pain Reports PAIN Reports, Vol 6, Iss 3, p e942 (2021) |
| ISSN: | 2471-2531 |
| DOI: | 10.1097/pr9.0000000000000942 |
| Popis: | How obesity affects pain sensitivity in pain-free individuals remains to be fully characterized. Quantitative sensory testing revealed that obese individuals had responses to heat and cold pain that were indistinguishable from nonobese individuals. Thus, obesity alone does not appear to be associated with amplification of nociceptive processing. Introduction: There is emerging evidence suggesting a relationship between obesity and chronic pain. Objectives: The aim of this study was to determine whether pain-free obese individuals display altered pain responses to acute noxious stimuli, thus raising the possibility of greater pain sensitivity and potential susceptibility for chronic pain development. Methods: Psychophysical and anthropometric data were collected from 38 individuals with an obese body mass index (BMI) classification (BMI ≥ 30) and 41 age/sex-matched individuals of a healthy BMI (BMI < 24.9). Because BMI may be an inaccurate index of obesity, additional anthropometric parameters of central adiposity and percent body fat were examined. Pain responses to suprathreshold noxious heat and cold stimuli were examined. Subjects provided pain intensity and unpleasantness ratings to noxious heat (49°C) applied at varying durations and locations (ventral forearm/lower leg). Cold pain ratings, thresholds, and tolerances were obtained after immersion of the hand in a cold-water bath (0–2°C). Between-group differences in pain responses, as well as relationships between pain responses and obesity parameters, were examined. Importantly, confounds that may influence pain such as anxiety, depression, impulsivity, sleepiness, and quality of life were assessed. Results: No between-group differences in pain sensitivity to noxious heat and cold stimuli were found. No relationships were found between central adiposity or body fat (percentage or distribution) and pain responses to noxious heat or cold stimuli. Conclusions: Obesity has minimal influence on pain sensitivity. Accordingly, it is unlikely that obesity alone increases susceptibility for chronic pain development through amplification of nociceptive processes. |
| Databáze: | OpenAIRE |
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