Opposite effect of negative and positive affect on stress procoagulant reactivity
| Autor: | Karl Frey, Dirk Hanebuth, Christoph Herrmann-Lingen, Daniel Preckel, Joachim E. Fischer, Brigitte M. Kudielka, Roland von Känel |
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| Rok vydání: | 2005 |
| Předmět: |
Adult
Male medicine.medical_specialty Hydrocortisone Blood Pressure Experimental and Cognitive Psychology Fibrinogen Statistics Nonparametric Negative affectivity Developmental psychology Coronary artery disease Behavioral Neuroscience chemistry.chemical_compound Heart Rate Internal medicine von Willebrand Factor medicine Trier social stress test Humans Reactivity (psychology) Blood Coagulation Life Style Demography Hemostasis Psychological Tests Factor VII Social Support Middle Aged medicine.disease Blood Coagulation Factors Affect Mood Endocrinology chemistry Cardiovascular Diseases Anxiety medicine.symptom Psychology Stress Psychological medicine.drug |
| Zdroj: | Physiology & Behavior. 86:61-68 |
| ISSN: | 0031-9384 |
| Popis: | Exaggerated procoagulant responses to acute mental stress may contribute to coronary thrombosis, and continuing low-grade systemic coagulation activation may link negative affect with the development of coronary artery disease. We investigated whether negative and positive affect and perceived social support would moderate stress procoagulant reactivity. Psychological functioning, exhaustion, negative affectivity, depression, anxiety, worrying, vigor, and social support were assessed in 27 apparently healthy men (mean age 47 ± 8 years) who underwent the 13-min Trier Social Stress Test combining preparation, speech, and mental arithmetic. Plasma levels of von Willebrand factor antigen (VWF:Ag), fibrinogen, factor VII clotting activity (FVII:C), FVIII:C, FXII:C, and D-dimer were measured immediately before and after stress. Acute stress elicited significant increases in hemodynamic, cortisol, and coagulant activity (p values |
| Databáze: | OpenAIRE |
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