Pharmaceutical interviews to overcome digestive artefacts on [ 99m Tc]Tc‐tetrofosmin myocardial perfusion scintigraphy
| Autor: | Oriane Nachar, Philippe Garrigue, Sophie Gabriel, Vincent Nail, Anaïs Moyon, Benjamin Guillet |
|---|---|
| Přispěvatelé: | Centre recherche en CardioVasculaire et Nutrition = Center for CardioVascular and Nutrition research (C2VN), Aix Marseille Université (AMU)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE) |
| Jazyk: | angličtina |
| Rok vydání: | 2021 |
| Předmět: |
[SDV]Life Sciences [q-bio]
Single-photon emission computed tomography Scintigraphy 030226 pharmacology & pharmacy single photon emission computed tomography 03 medical and health sciences pharmacist consultation 0302 clinical medicine Myocardial perfusion scintigraphy radiopharmacy medicine scintigraphy Pharmacology (medical) 030212 general & internal medicine ComputingMilieux_MISCELLANEOUS Pharmacology medicine.diagnostic_test business.industry Dipyridamole Fresh water Scintigraphic imaging Tracer uptake Nuclear medicine business Perfusion medicine.drug |
| Zdroj: | Journal of Clinical Pharmacy and Therapeutics Journal of Clinical Pharmacy and Therapeutics, 2021, 46 (5), pp.1480-1483. ⟨10.1111/jcpt.13418⟩ |
| ISSN: | 0269-4727 1365-2710 |
| DOI: | 10.1111/jcpt.13418⟩ |
| Popis: | International audience; What is known and objectives Poor image quality was randomly seen in [Tc-99m]Tc-tetrofosmin myocardial perfusion scintigraphic imaging. The interference hampered or even precluded medical interpretation. Our objective was to identify the cause of the random interferences.Methods Out of 40 patients planned for [Tc-99m]Tc-tetrofosmin MPS, 36 presented normal tracer uptake and 4 exhibited subdiaphragmatic artefacts. Pharmaceutical interviews (P.I.) were set up to formally identify aetiologies of subdiaphragmatic uptake of [Tc-99m]Tc-tetrofosmin. Patients were questioned about their diet and current drug treatments. Results and discussion P.I. led to identification of dipyridamole as the cause of the artefacts. The systematic ingestion of a solid 25-gram high-fat snack bar and a glass of fresh water was introduced immediately after the injection of dipyridamole in 12 other patients undergoing [Tc-99m]Tc-tetrofosmin MPS. None of the 12 patients presented subdiaphragmatic artefacts. What is new and conclusion P.I. identified the cause of poor scintigraphic images to allow improved diagnoses. |
| Databáze: | OpenAIRE |
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