Performance of a rapid molecular test to detect Chlamydia trachomatis and Neisseria gonorrhoeae in women with pelvic inflammatory disease
| Autor: | Jordina Munrós, Borja García-Lorenzo, Míriam J. Álvarez-Martínez, Andrea Vergara, Eduardo Bataller, Jordi Bosch |
|---|---|
| Rok vydání: | 2021 |
| Předmět: |
0301 basic medicine
Microbiology (medical) medicine.medical_specialty Concordance 030106 microbiology Chlamydia trachomatis medicine.disease_cause 03 medical and health sciences 0302 clinical medicine Disease severity Internal medicine Pelvic inflammatory disease medicine Humans 030212 general & internal medicine business.industry Incidence (epidemiology) Incidence Chlamydia Infections Standard technique Neisseria gonorrhoeae Cost analysis Female business Pelvic Inflammatory Disease |
| Zdroj: | Enfermedades infecciosas y microbiologia clinica (English ed.). 40(7) |
| ISSN: | 2529-993X |
| Popis: | Objective The aim of this study was to investigate the prevalence of Chlamydia trachomatis (CT) and Neisseria gonorrhoeae (NG) in women with pelvic inflammatory disease (PID) and the usefulness and cost-effectiveness of a rapid molecular test for the diagnosis and clinical management of PID. Methods This observational study included 75 patients with mild-to-moderate PID (n = 33), severe PID (n = 29) and non-specific lower abdominal pain (NSAP) (n = 13). CT/NG infections were analyzed using a standard and a rapid test. A cost analysis was carried out. Results Samples of 19 patients (25.3%) were CT/NG positive. Concordance between rapid and standard tests was 100%. No significant differences were observed in the incidence of CT/NG in mild-to-moderate compared to severe PID. Costs differed according only to disease severity. Conclusions Rapid molecular tests could help with the diagnosis of PID in sexually active women in clinical settings in which a standard technique is not available. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|
Full Text from ScienceDirect