Oxalate Content of Enteral Nutrition Formulas
| Autor: | Kristina L. Penniston, David J. Beshensky, Ibrahim A. M. Saeed, Riley J. Medenwald, Leema M. John, Sarah N. Johnson, Eve A. Palmer |
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| Rok vydání: | 2019 |
| Předmět: |
medicine.medical_specialty
Calcium oxalate Nutritional Status Gastroenterology Oxalate 03 medical and health sciences chemistry.chemical_compound 0302 clinical medicine Enteral Nutrition 030225 pediatrics Internal medicine medicine Humans Intubation Gastrointestinal Food Formulated Hyperoxaluria Oxalates business.industry Nutritional status medicine.disease Parenteral nutrition chemistry Pediatrics Perinatology and Child Health 030211 gastroenterology & hepatology Kidney stones High incidence business |
| Zdroj: | Journal of pediatric gastroenterology and nutrition. 69(5) |
| ISSN: | 1536-4801 |
| Popis: | Patients requiring oral and/or enteral nutrition support, delivered via nasogastric, gastric, or intestinal routes, have a relatively high incidence of calcium oxalate (CaOx) kidney stones. Nutrition formulas are frequently made from corn and/or or soy, both of which contain ample oxalate. Excessive oxalate intake contributes to hyperoxaluria (45 mg urine oxalate/day) and CaOx stones especially when unopposed by concomitant calcium intake, gastrointestinal malabsorption is present, and/or oxalate degrading gut bacteria are limiting or absent. Our objective was to assess the oxalate content of commonly used commercial enteral nutrition formulas.Enteral nutrition formulas were selected from the formulary at our clinical inpatient institution. Multiple samples of each were assessed for oxalate concentration with ion chromatography.Results from 26 formulas revealed highly variable oxalate concentration ranging from 4 to 140 mg oxalate/L of formula. No definitive patterns for different types of formulas (eg, flavored vs unflavored, high protein vs not) were evident. Coefficients of variation for all formulas ranged from 0.68% to 43% (mean ± SD 19% ± 12%; median 18%).Depending on the formula and amount delivered, patients requiring nutrition support could obtain anywhere from 12 to 150 mg oxalate/day or more and are thus at risk for hyperoxaluria and CaOx stones. |
| Databáze: | OpenAIRE |
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