Chemical and activity investigation on metabolites produced by an endophytic fungi Psathyrella candolleana from the seed of Ginkgo biloba
| Autor: | Shengli Yang, Yun Pan, Weihong Zheng |
|---|---|
| Rok vydání: | 2019 |
| Předmět: |
biology
010405 organic chemistry Chemistry Ginkgo biloba fungi Organic Chemistry Ethyl acetate food and beverages Plant Science Endophytic fungus biology.organism_classification 01 natural sciences Biochemistry Plant use of endophytic fungi in defense 0104 chemical sciences Analytical Chemistry carbohydrates (lipids) 010404 medicinal & biomolecular chemistry Chromatographic separation chemistry.chemical_compound Psathyrella candolleana Botany |
| Zdroj: | Natural Product Research. 34:3130-3133 |
| ISSN: | 1478-6427 1478-6419 |
| DOI: | 10.1080/14786419.2019.1607335 |
| Popis: | An endophytic fungus that can produce flavonoids was isolated from the seed of Ginkgo biloba cultured in Czapek-Dox medium and chromatographic separation of the ethyl acetate extract of the broth and mycelium led to the isolation of ergosterol (1), 2′-hydroxychalcone (2), myristic acid (3), cis-9-octadecenoamide (4), quercetin (5), carboxybenzene (6), uracil (7) and nicotinamide (8). This study is the first to report of the isolation of the endophytic fungus Psathyrella candolleana from the seed of Ginkgo biloba with complete assignments of 1–8. Compound (5) exhibited strong antioxidant activity of diphenyl picryl hydrazinyl (CL50 14.538 μg/mg) and compounds (5), (6) and (8) have antibacterial activity against Staphylococcus aureus (MIC 0.3906, 0.7812 and 6.25 mg/mL). |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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