Trends of neglected Plasmodium species infection in humans over the past century in India
| Autor: | Abhinav Sinha, Amit Sharma, Rini Chaturvedi, Nimita Deora, Suhel Parvez, Deepam Bhandari |
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| Rok vydání: | 2020 |
| Předmět: |
Veterinary medicine
P. ovale Plasmodium vivax malaria CDC Centres for Disease Control and Prevention Plasmodium malariae P. knowlesi Malaria elimination parasitic diseases medicine PCR Polymerase Chain Reaction AL Artemether-Lumefantrine P. malariae Plasmodium species lcsh:R5-920 biology Public Health Environmental and Occupational Health SP Sulfadoxine-Pyrimethamine Plasmodium falciparum DBS Dried Blood Spots Neglected Plasmodium species medicine.disease biology.organism_classification Plasmodium ovale AS Artesunate Infectious Diseases POC Point of Care Plasmodium knowlesi G6PD Glucose-6-Phosphate Dehydrogenase RDT Rapid Diagnostic Tests lcsh:Medicine (General) LAMP Loop-mediated isothermal amplification ACT Artemisinin-based combination therapy IV intravenous Malaria Research Paper |
| Zdroj: | One Health One Health, Vol 11, Iss, Pp 100190-(2020) |
| ISSN: | 2352-7714 |
| DOI: | 10.1016/j.onehlt.2020.100190 |
| Popis: | Background Efforts for malaria elimination in India focus solely on the more prevalent human malaria parasites of Plasmodium falciparum (Pf) and Plasmodium vivax (Pv). The three non-Pf/Pv species - Plasmodium malariae (Pm), Plasmodium ovale (Po) and Plasmodium knowlesi (Pk) are seldom studied though they are often present as mixed infections with Pf/Pv and thus may be misdiagnosed. This study provides a comprehensive landscape of Pm, Po, and Pk infections from 1930 to 2020. Methodology We systematically searched for published literature on Pm, Po, and Pk in India from PubMed database and collated data from 35 studies. The data, starting from 1930, were mapped decade-wise across India. The prevalence of the three neglected Plasmodium species and their proportional contribution to reported Plasmodium mixed-infection were also calculated and analysed. Principal findings Amongst the three non-Pf/Pv species, Pm infections have been reported in greater numbers across India and were mostly mono-infections till 1980. From 1983 onwards, reports of Pm mixed infections with Pf/Pv started to emerge. In contrast, reports on occurrence of Po are still rare barring few mixed infection studies. Further, Pk mono- and mixed cases were first reported in 2004 in India and Pk now has been found reported from four Indian states. Conclusion This is the first account of country-wide assimilation of reported malaria parasite species data that covers Pm, Po, and Pk infection profiles from 1930 to 2020. This study illustrates the need to survey all 5 human malaria parasite species in India and to target them collectively during the malaria elimination phase. Highlights • Current malaria elimination program in India focuses only on P. falciparum and P. vivax. • The 3 Plasmodium species- Pm, Po, and Pk are rarely studied and often misdiagnosed. • The overall prevalence of Pm is higher than Po and Pk in India. • Pm with Pf mixed infection contributes the highest proportion for the last three decades. • For malaria elimination, a complete coverage of all 5 Plasmodium species should be implemented. |
| Databáze: | OpenAIRE |
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