Zinc transporter 7 is located in the cis-Golgi apparatus of mouse choroid epithelial cells
| Autor: | Hui-Ling Gao, Zhan-You Wang, Zhi-Hong Chi, Annica Dahlström, Liping Huang, Xin Wang |
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| Rok vydání: | 2006 |
| Předmět: |
Male
Golgi Apparatus chemistry.chemical_element Zinc ZINC TRANSPORTER 7 Mice symbols.namesake Microscopy Electron Transmission medicine Animals Cellular localization biology General Neuroscience Epithelial Cells Golgi apparatus Immunohistochemistry Epithelium Cell biology medicine.anatomical_structure Biochemistry chemistry Cytoplasm Choroid Plexus symbols biology.protein Choroid plexus Carrier Proteins Immunostaining |
| Zdroj: | NeuroReport. 17:1807-1811 |
| ISSN: | 0959-4965 |
| DOI: | 10.1097/01.wnr.0000239968.06438.c5 |
| Popis: | The cellular localization of zinc transporter 7 protein in the mouse choroid plexus was examined in this study. Zinc transporter 7 immunoreactive cells were detected in the third, lateral, and fourth ventricles of CD-1 mouse brain. Distinct zinc transporter 7 immunoreactivity was concentrated in the perinuclear regions of the positive cells. The results from zinc autometallography showed that zinc-positive grains were also predominantly located in the perinuclear areas. Ultrastructural localization showed that zinc transporter 7 immunostaining was predominantly present in the membrane and cisternae of the cis-Golgi networks and some vesicle compartments. The results support the notion that zinc transporter 7 may participate in the transport of the cytoplasmic zinc into the Golgi apparatus, and may be involved in local packaging of zinc-binding proteins in the mouse choroid plexus. |
| Databáze: | OpenAIRE |
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