Ocular transmission and manifestation for coronavirus disease: a systematic review
| Autor: | Hanan Alkozi, Walead Alghamdi, Ahmed Almazroa, Suhailah Alamri, Altaf Khan, Balsam Alabdulkader |
|---|---|
| Rok vydání: | 2021 |
| Předmět: |
medicine.medical_specialty
Health (social science) Coronavirus disease 2019 (COVID-19) viruses Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) coronavirus Review Article Disease medicine.disease_cause 03 medical and health sciences ocular manifestation 0302 clinical medicine nasopharyngeal swabs conjunctival swabs conjunctivitis Humans Medicine 030212 general & internal medicine Respiratory system skin and connective tissue diseases Tropism Coronavirus SARS-CoV-2 business.industry Transmission (medicine) fungi Public Health Environmental and Occupational Health COVID-19 tears virus diseases ocular transmission General Medicine Dermatology body regions AcademicSubjects/MED00390 Cross-Sectional Studies 030221 ophthalmology & optometry Tears business Conjunctiva |
| Zdroj: | International Health |
| ISSN: | 1876-3405 1876-3413 |
| Popis: | Background There is currently a lack of information regarding ocular tropism and the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Globally, the cumulative number of coronavirus disease 2019 (COVID-19) cases is increasing daily. Thus the potential for ocular transmission and manifestations of SARS-CoV-2 requires more investigation. Methods A systematic search of electronic databases for ocular transmission and manifestations of SARS-CoV-2 was performed. Pooled cross-sectional studies were used for conducting a meta-analysis to estimate the prevalence of ocular transmission of SARS-CoV-2 to the respiratory system and ocular manifestations (associated symptoms) of SARS-CoV-2. Results The highest prevalence of SARS-CoV-2-positive tears using reverse transcription polymerase chain reaction was found to be 7.5%. However, the highest prevalence of ocular conjunctivitis associated with SARS-CoV-2 was 32%. Thus, SARS-CoV-2 can evidently infect the eye, as revealed in the conjunctival secretions of COVID-19 patients. Conclusion The available data reflect the influence of the ocular structure on SARS-CoV-2. The analysis showed that ocular manifestation is an indication for SARS-CoV-2, particularly conjunctivitis. Moreover, there is no evidence that the ocular structure can be an additional path of transmission for SARS-CoV-2, however, it warrants further investigation. |
| Databáze: | OpenAIRE |
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