Detection of interleukin 10 in cerebrospinal fluid of patients with subacute sclerosing panencephalitis
| Autor: | Mariana Viegas, R. A. Diez, Alicia Mistchenko, M. C. Fornari, P. R. Barrero |
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| Rok vydání: | 2005 |
| Předmět: |
Male
Simian Measles Subacute sclerosing panencephalitis Interferon-gamma Cellular and Molecular Neuroscience Th2 Cells Acquired immunodeficiency syndrome (AIDS) Virology medicine Humans Age of Onset biology Molecular epidemiology Transmission (medicine) business.industry Infant virus diseases biology.organism_classification medicine.disease Interleukin-10 Interleukin 10 Neurology Measles virus Child Preschool Immunology Female Interleukin-4 Subacute Sclerosing Panencephalitis Neurology (clinical) Viral disease business |
| Zdroj: | Journal of NeuroVirology. 11:66-69 |
| ISSN: | 1355-0284 |
| DOI: | 10.1080/13550280590901769 |
| Popis: | A significant effort has been put into identifying the origin of HIV, tracking its spread, and mapping its distribution. This effort is of particular importance in Africa, where the AIDS epidemic is genetically most diverse, where prevalence reaches its highest levels, and where HIV had its origins in cross-species transmission from non-human primates to man. In this article, we summarize the molecular epidemiology of HIV in Africa, from both a historical and modern perspective. There are marked differences in the local diversity and in the rate of epidemic expansion in different regions of Africa. Understanding the distribution of genetic forms of HIV can be used to tailor vaccine strategies to specific regions and nations. Finally, we review the relationship of HIV lineages to related simian retroviruses and the evolutionary history and the origins of the HIV epidemic. |
| Databáze: | OpenAIRE |
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