Triglyceride-Glukose Index Predicts Adverse Events in Patients with Acute Coronary Syndrome: A Meta-Analysis of Cohort Studies
Autor: | Juying Li, Lin Luo, Ling Ren, Cheng Chang |
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Rok vydání: | 2021 |
Předmět: |
Blood Glucose
Acute coronary syndrome medicine.medical_specialty Endocrinology Diabetes and Metabolism medicine.medical_treatment Clinical Biochemistry Long Term Adverse Effects 030209 endocrinology & metabolism 030204 cardiovascular system & hematology Biochemistry Cohort Studies 03 medical and health sciences 0302 clinical medicine Endocrinology Risk Factors Internal medicine medicine Humans Myocardial infarction Acute Coronary Syndrome Triglycerides business.industry Incidence (epidemiology) Incidence Biochemistry (medical) Percutaneous coronary intervention General Medicine medicine.disease Confidence interval Cardiovascular Diseases Meta-analysis Relative risk business Biomarkers Cohort study |
Zdroj: | Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme. 53(9) |
ISSN: | 1439-4286 |
Popis: | The triglyceride-glucose (TyG) index, a recently proposed indicator for insulin resistance, has been related with cardiovascular risks. We aimed to summarize the association between TyG index and incidence of major adverse cardiovascular events (MACEs) in patients with acute coronary syndrome (ACS). Cohort studies demonstrating the association between TyG index and incidence of MACEs in ACS patients with multivariate adjusted analyses were identified by search of PubMed, Embase, and Web of Science databases. A random-effekt model incorporating the heterogeneity was applied to pool the results. Eight cohort studies with 19 611 participants were included. Results showed that compared to those with the lowest category of TyG index, ACS patients with the highest category of TyG index were independently associated with higher risk of MACEs [risk ratio (RR): 1.94, 95% confidence interval (CI): 1.47–2.56, I2=85%, p |
Databáze: | OpenAIRE |
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