CD200/CD200R paired potent inhibitory molecules regulating immune and inflammatory responses; Part II: CD200/CD200R potential clinical applications
| Autor: | Jan Krejsek, Katerina Kondelkova, Pavel Kunes, Drahomira Holmannova, Martina Kolackova, Andrjos Ctirad |
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| Rok vydání: | 2012 |
| Předmět: |
lcsh:Medicine
Inflammation Context (language use) CD200R Biology Self-tolerance Autoimmune Diseases Immune system Antigens CD Central Nervous System Diseases Transplantation Immunology Neoplasms medicine Animals Humans Receptor lcsh:R Immunity Immunoregulation General Medicine medicine.disease Virus Diseases CD200 Rheumatoid arthritis Immunology Self Tolerance medicine.symptom Alzheimer's disease CD-200 |
| Zdroj: | Acta Medica, Vol 55, Iss 2, Pp 59-65 (2012) |
| ISSN: | 1211-4286 |
| Popis: | CD200 and its receptor were recognized as having the multiple immunoregulatory functions. Their immunoregulatory, suppressive, and tolerogenic potentials could be very effectively exploited in the treatment of many diseases, e.g. Alzheimer disease, rheumatoid arthritis, and allergy to name only some. Many research projects are aimed to develop clinically valuable methods being based on the structure and function of these paired molecules. In this review, we would like to introduce CD200/CD200R functions in a clinical context. |
| Databáze: | OpenAIRE |
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