The relationship between mean arterial pressure and decreased glomerular filtration rate in rural areas of Northeast China
| Autor: | Hongmei Yang, Yingxian Sun, Xingang Zhang, Shasha Yu, Wenna Li, Ying Zhou, Xiaofan Guo, Liqiang Zheng, Zhao Li |
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| Jazyk: | angličtina |
| Předmět: |
Nephrology
Adult Blood Glucose Male Rural Population medicine.medical_specialty Mean arterial pressure China Alcohol Drinking Cross-sectional study Population Renal function Motor Activity Rural areas Hemoglobins Sex Factors Internal medicine medicine Prevalence Humans Arterial Pressure Renal Insufficiency education Triglycerides Aged education.field_of_study Relationship business.industry Cholesterol HDL Smoking Age Factors Cholesterol LDL Middle Aged Uric Acid Blood pressure Endocrinology Decreased glomerular filtration rate Cross-Sectional Studies Renal blood flow Cardiology Income Educational Status Female business Research Article Glomerular Filtration Rate |
| Zdroj: | BMC Nephrology |
| ISSN: | 1471-2369 |
| DOI: | 10.1186/s12882-015-0115-4 |
| Popis: | Background Low mean arterial pressure (MAP) can cause low renal blood flow and damage the kidneys. However, in the general population, it remains unclear whether or not decline in renal function is related to MAP. The present study examined the relationship between MAP and decreased glomerular filtration rate(GFR) in participans aged ≥35 years from the Liaoning province of China. Methods A total of 11345 representative individuals aged ≥ 35 years was selected and a cross-sectional survey was conducted from January 2012 to August 2013 to describe the gender-specific prevalence and factors associated with decreased GFR in rural areas of Liaoning Province. Results Men with decreased eGFR (eGFR 112.2 mmHg versus ≤ 93.8 mmHg had ORs for decreased eGFR of 2.367 (95 % CI: 1.248 to 4.488) .After multivariable adjustment, an MAP of >112.2 mmHg versus ≤93.8 mmHg had an OR for decreased eGFR of 3.249 (95 % CI:1.394 to 7.575) in men, whereas in women, MAP was not associated with decreased eGFR. Conclusions MAP was associated with decreased eGFR in men, while in women MAP was not associated with decreased eGFR. These findings provide some evidence that a different adaptive response to renal regulation may exist in males and females. |
| Databáze: | OpenAIRE |
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